Indigo

Drug ingredient

CAS 482-89-3

This drug ingredient has classified U.S. production volumes. EPA withholds the number as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$9M

Top sourceIndia 67%

At least one company claimed its 2019 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2019. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 320415 · basket

EPA reports by year

2019: US production Confidential · Imports Confidential

These shares come from HS customs code 320415, which covers 10 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IN 67%IndiaCN 14%ChinaNL 9%NetherlandsJP 5%JapanID 2%Indonesia

Spain
Turkey
Luxembourg

EPA-registered importers (1)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Aceto Us

3 FDA-registered drug labelers

Bestmade Natural Products

BM PRIVATE LIMITED

Hahnemann Laboratories, INC.

Why It Matters

Sectors

HealthTextiles

Downstream Uses

Appears in 3 drug and cosmetic product listings (FDA).

•Indigo
•CINA
•Bestmade Natural Products BM238

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

•Pigment in Synthetic Dye and Pigment Manufacturing (100%)Processing as a reactant

Chemical Identity

CAS482-89-3

PubChem CID10215

DTXSIDDTXSID3026279

FormulaC16H10N2O2

Mol. Weight262.26 g/mol

SMILESC1=CC=C2C(=C1)C(=C(N2)C3=NC4=CC=CC=C4C3=O)O

Data Sources

EPA CompTox (DSSTox) · DTXSID3026279Retrieved 2026-04-06
PubChem · compound 10215Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2019 · Retrieved 2026-10-04
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Indigo (CAS 482-89-3) https://chemicalindependence.com/chemical/482-89-3/ EPA CompTox (DSSTox): DTXSID3026279. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID3026279 PubChem: 10215. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/10215 EPA Chemical Data Reporting: 482-89-3. Reporting year: 2019. https://www.epa.gov/chemical-data-reporting FDA National Drug Code directory: CAS 482-89-3. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 320415 for CAS 482-89-3. Reporting year: 2024. https://usatrade.census.gov/