santonin

Drug ingredient

CAS 481-06-1

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$286M

Top sourceChina 48%

EPA lists this chemical as inactive, meaning no company reported making, importing or processing it in the US from 2006 to 2016.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293220 · basket

These shares come from HS customs code 293220, which covers 151 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 48%ChinaIN 15%IndiaJP 7%JapanGB 7%United KingdomCH 7%Switzerland

Mexico
Austria
Indonesia
Czech Republic
Slovakia
Malaysia
Israel
Poland
Vietnam
Ukraine
South Africa
Singapore
Russia
Lithuania
Hungary
Belarus
Brazil
Australia

9 FDA-registered drug labelers

Apex Energetics Inc.

Bestmade Natural Products

BM PRIVATE LIMITED

Boiron

Energique, Inc.

NET Remedies

Newton Laboratories, Inc.

OHM PHARMA INC.

Vitality Works, Inc.

Why It Matters

Sectors

Health

Downstream Uses

Appears in 11 drug and cosmetic product listings (FDA).

•Vermiclear
•Para-Si
•N10 Paraklenz
•CINA
•OHM Parasites
•Bestmade Natural Products BM43
•Para Solve
•Bestmade Natural Products BM256

Show all 11

•Brain Supp
•Santoninum
•Bestmade Natural Products BM238

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Chemical Identity

CAS481-06-1

PubChem CID221071

DTXSIDDTXSID7045312

FormulaC15H18O3

Mol. Weight246.3 g/mol

SMILESCC1C2CCC3(C=CC(=O)C(=C3C2OC1=O)C)C

Data Sources

PubChem · compound 221071Retrieved 2026-04-07
EPA TSCA InventoryRetrieved 2026-04-24
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

← Back to Dashboard ← Back to Health

Brief citations

santonin (CAS 481-06-1) https://chemicalindependence.com/chemical/481-06-1/ PubChem: 221071. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/221071 EPA TSCA Inventory: CAS 481-06-1. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293220 for CAS 481-06-1. Reporting year: 2024. https://usatrade.census.gov/