Sorafenib tosylate

Drug ingredient

CAS 475207-59-1

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$1.3B

Top sourceChina 32%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293339 · basket

These shares come from HS customs code 293339, which covers 397 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 32%ChinaIN 15%IndiaDE 10%GermanyBE 9%BelgiumCH 8%Switzerland

Taiwan
Ukraine
Sweden
Argentina
Canada
Finland
Malta
Israel
Netherlands
Denmark
United Arab Emirates
Mexico
Brunei
Slovakia
Australia
South Africa
Poland
Latvia
Lithuania
Estonia
Slovenia
Czech Republic
Croatia
Hong Kong

10 FDA-registered drug labelers

Aurobindo Pharma Limited

AX Pharmaceutical Corp

Dr.Reddys Laboratories Inc

Granules India Ltd

Hetero Labs Limited

MSN Laboratories Private Limited

Mylan Pharmaceuticals Inc.

Natco Pharma Limited

Teva Pharmaceuticals, Inc.

Yabao Pharmaceutical Group Co., Ltd.

Why It Matters

Sectors

Health

Downstream Uses

Appears in 2 drug and cosmetic product listings (FDA).

•Sorafenib
•Sorafenib Tosylate

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$2.08/gAaron Chemicals LLC

CountryHong Kong

Pack$208.00 / 100 g

Purity99%

Vendors21 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

20 more vendors

Vendor	Country	$/g	Pack	Purity
Angene Chemical	China → Hong Kong	$2.11	100 g	99%
A2B Chem LLC	United States	$3.55	500 g	98%
AA BLOCKS	United States	$3.75	500 g	98%
Combi-Blocks, Inc.	United States	$4.20	100 g	97%
Ambeed, Inc.	United States	$6.00	25 g	98%
AstaTech, Inc	United States	$8.10	10 g	97%
AK Scientific Specialized	United States	$8.60	25 g	95%
Cayman Europe	Estonia	$10.76	50 g	98%
AK Scientific, Inc.	United States	$12.04	25 g	98%
MedKoo Biosciences, Inc	United States	$37.50	20 g	98%
Biopharma PEG Scientific Inc.	United States	$92.00	5 g	97%
TargetMol Chemicals	China → United States	$96.00	1 g	99.94%
Molnova	China	$120.00	500 mg	99%
Angene International Limited	United States	$128.60	5 g	99%
MedChemExpress MCE	Sweden	$215.38	500 mg	99.98%
Apexbio Technology LLC	United States	$860.00	200 mg	99.79%
ChemFaces	China	$1500.00	20 mg	98%
Axon Medchem	Netherlands	$3360.00	50 mg	99%
Angene	China → Hong Kong	$4266.67	30 mg	99%
Key Organics Ltd.	United Kingdom	$11700.00	10 mg	97%

Chemical Identity

CAS475207-59-1

PubChem CID406563

DTXSIDDTXSID9047839

FormulaC28H24ClF3N4O6S

Mol. Weight637 g/mol

SMILESCC1=CC=C(C=C1)S(=O)(=O)O.CNC(=O)C1=NC=CC(=C1)OC2=CC=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F

Data Sources

PubChem · compound 406563Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Sorafenib tosylate (CAS 475207-59-1) https://chemicalindependence.com/chemical/475207-59-1/ PubChem: 406563. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/406563 FDA National Drug Code directory: CAS 475207-59-1. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293339 for CAS 475207-59-1. Reporting year: 2024. https://usatrade.census.gov/