orphenadrine citrate

Drug ingredient

CAS 4682-36-4

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 4682-36-4
US productionNot reported
Import value, 2024$197M
Top sourceChina 36%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 292219 · basket

These shares come from HS customs code 292219, which covers 167 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
CN 36%ChinaIT 15%ItalyDE 14%GermanyIN 7%IndiaHU 5%Hungary
27 FDA-registered drug labelers
A-S Medication Solutions
Actavis Pharma, Inc.
Advanced Rx Pharmacy of Tennessee, LLC
Atland Pharmaceuticals, LLC
Bryant Ranch Prepack
Fagron Inc
Galt Pharmaceuticals, LLC
Hikma Pharmaceuticals USA Inc.
Lake Erie Medical DBA Quality Care Products LLC
Lupin Pharmaceuticals, Inc.
Medisca Inc.
Northwind Health Company, LLC
NuCare Pharmaceuticals, Inc.
PD-Rx Pharmaceuticals, Inc.
Poly Pharmaceuticals, Inc.
Preferred Pharmaceuticals, Inc.
PROCOS S.p.A.
Professional Compounding Centers of America
Professional Compounding Centers of America dba PCCA
Proficient Rx LP
R.L.Fine Chem Private Limited
RedPharm Drug
REMEDYREPACK INC.
Sagent Pharmaceuticals
Sandoz Inc
St. Mary's Medical Park Pharmacy
W. R. GRACE & CO.-CONN.

Why It Matters

Sectors
Health
Downstream Uses

Appears in 6 drug and cosmetic product listings (FDA).

  • •Orphenadrine Citrate
  • •Orphenadrine Citrate ER
  • •Orphenadrine Citrate, Aspirin and Caffeine
  • •Norgesic Forte
  • •Orphengesic Forte
  • •Norgesic
FDA Shortage Status
No FDA shortage records

Vendor Pricing

$5.60/gA2B Chem LLC
CountryUnited States
Pack$140.00 / 25 g
Purity98%
Vendors13 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

Chemical Identity

CAS4682-36-4
PubChem CID83823
DTXSIDDTXSID8044678
FormulaC24H31NO8
Mol. Weight461.5 g/mol
SMILESCC1=CC=CC=C1C(C2=CC=CC=C2)OCCN(C)C.C(C(=O)O)C(CC(=O)O)(C(=O)O)O

Data Sources

Brief citations

orphenadrine citrate (CAS 4682-36-4) https://chemicalindependence.com/chemical/4682-36-4/ PubChem: 83823. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/83823 FDA National Drug Code directory: CAS 4682-36-4. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 292219 for CAS 4682-36-4. Reporting year: 2024. https://usatrade.census.gov/