Lithium 3-carboxy-5-sulfobenzoate

CAS 46728-75-0

U.S. production volumes are classified as confidential business information.

Molecular structure of 46728-75-0 — 1 Li⁺

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$316M

Top sourceSouth Korea 19%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 291739 · basket

EPA reports by year

2023: US production Confidential · Imports Confidential
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 291739, which covers 103 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

KR 19%South KoreaCN 19%ChinaIN 18%IndiaES 13%SpainCA 9%Canada

Netherlands
Malaysia
Colombia
Switzerland
Turkey
Germany
Peru
Brazil
Sweden
Belgium
Denmark
Czech Republic
Ukraine
Hong Kong

EPA-registered manufacturers (1)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Futurefuel

Why It Matters

Sectors

Core Chemicals

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

Used in 1 sector as 2 functional roles.

•Intermediate in All Other Basic Organic Chemical ManufacturingProcessing as a reactant
•Monomers in All Other Basic Organic Chemical Manufacturing (100%)Processing as a reactant

Chemical Identity

CAS46728-75-0

PubChem CID23688987

DTXSIDDTXSID5044819

FormulaC8H5LiO7S

Mol. Weight252.2 g/mol

SMILES[Li+].C1=C(C=C(C=C1C(=O)[O-])S(=O)(=O)O)C(=O)O

Data Sources

EPA CompTox (DSSTox) · DTXSID5044819Retrieved 2026-04-06
PubChem · compound 23688987Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Lithium 3-carboxy-5-sulfobenzoate (CAS 46728-75-0) https://chemicalindependence.com/chemical/46728-75-0/ EPA CompTox (DSSTox): DTXSID5044819. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID5044819 PubChem: 23688987. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/23688987 EPA Chemical Data Reporting: 46728-75-0. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 46728-75-0. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 291739 for CAS 46728-75-0. Reporting year: 2024. https://usatrade.census.gov/