Dapagliflozin

Drug ingredient

CAS 461432-26-8

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$3.5B

Top sourceIreland 57%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293299 · basket

These shares come from HS customs code 293299, which covers 229 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IE 57%IrelandNL 24%NetherlandsCH 8%SwitzerlandCN 5%ChinaIT 2%Italy

United Kingdom
Japan
Germany
Spain
Israel
Canada
Brazil
Vietnam
Ukraine
New Zealand
Belgium
Mexico
Singapore
Taiwan
South Korea
Sweden
South Africa
Egypt
Indonesia
Lithuania
Finland
Hungary
Czech Republic
Hong Kong
Malaysia
Slovakia
Australia
Russia
Jordan
Latvia
Argentina
Slovenia
Malta
Poland
Denmark
Austria

15 FDA-registered drug labelers

Alivus Life Sciences Limited

Aurobindo Pharma Limited

Biocon Limited

Dr.Reddy's Laboratories Limited

Granules India Limited

Harman Finochem Limited

Honour Lab Limited

Jiangsu Hansoh Pharmaceutical Group Co., Ltd.

M/s. Lee Pharma Limited

Metrochem API Private Limited

MSN Laboratories Private Limited

Optimus Drugs Private Limited

SK BIOTEK IRELAND LIMITED

SUN PHARMACEUTICAL IND LTD, MUMBAI

USV Private Limited

Why It Matters

Sectors

Health

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Chemical Identity

CAS461432-26-8

PubChem CID9887712

DTXSIDDTXSID20905104

FormulaC21H25ClO6

Mol. Weight408.9 g/mol

SMILESCCOC1=CC=C(C=C1)CC2=C(C=CC(=C2)C3C(C(C(C(O3)CO)O)O)O)Cl

Data Sources

PubChem · compound 9887712Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Dapagliflozin (CAS 461432-26-8) https://chemicalindependence.com/chemical/461432-26-8/ PubChem: 9887712. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/9887712 FDA National Drug Code directory: CAS 461432-26-8. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293299 for CAS 461432-26-8. Reporting year: 2024. https://usatrade.census.gov/