Cyanoguanidine
CAS 461-58-5
U.S. production volumes are classified as confidential business information.
US productionCBI
Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.
Import value, 2024$26M
Top sourceChina 56%
At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.
Why supply is unknownProduction is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023.
Where It Comes From
Customs basis: HS 292620 · exact
EPA reports by year
- 2023
- US production Confidential · Imports Confidential
- 2019
- US production Confidential · Imports Confidential
Source Countries
Country of origin for US imports, from Census customs data (2024).
CN 56%ChinaDE 44%Germany
- United Kingdom
- South Korea
- Canada
- Switzerland
- India
Domestic parents -- activity not disclosed (7)
EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.
American River Brokerage
Archroma U.S
Arxada
Henkel
Phibro Animal Health
Show all 7
Pht International
Synsus Private Label Partners
EPA-registered importers (10)
Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.
3M
Alzchem
Autoliv Promontory
Brenntag
Capital Resin
Show all 10
Huntsman
Koch Industries
The Chemical
The Sherwin Williams
Wego Chemical Group
Why It Matters
Sectors
DefenseAgricultureEnergyElectronicsTransportationMetals & MiningPlastics & RubberTextilesConsumer ProductsPaints & CoatingsCore Chemicals
Downstream UsesNot recorded
FDA Shortage Status
Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."
No FDA shortage records
Industrial Uses
Used in 13 sectors as 9 functional roles.
- •Intermediate in All Other Basic Organic Chemical Manufacturing (15%)Processing—incorporation into formulation, mixture, or reaction product
- •Intermediate in All Other Chemical Product and Preparation Manufacturing (1%)Processing as a reactant
- •Hardener in All Other Chemical Product and Preparation Manufacturing (20%)Processing as a reactant
- •Fixing agent (mordant) in Textiles, apparel, and leather manufacturing (100%)Processing as a reactant
- •Soil amendments (fertilizers) in Pesticide, Fertilizer, and Other Agricultural Chemical Manufacturing (100%)Processing—repackaging
- •Fixing agent (mordant) in Synthetic Dye and Pigment Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Intermediate in Plastics Material and Resin ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Hardener in Transportation Equipment ManufacturingProcessing—incorporation into article
- •Hardener in Paint and Coating Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Hardener in Electrical Equipment, Appliance, and Component ManufacturingProcessing—incorporation into article
- •Hardener in Miscellaneous ManufacturingProcessing—incorporation into article
- •Chemical reaction regulator in Paint and Coating Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Chemical reaction regulator in Oil and Gas Drilling, Extraction, and Support activities (100%)Processing as a reactant
- •Chemical reaction regulator in Transportation Equipment Manufacturing (0%)Processing as a reactant
- •Intermediate in Synthetic Dye and Pigment Manufacturing (100%)Processing as a reactant
- •Monomers in All Other Basic Organic Chemical Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Dye in Textiles, apparel, and leather manufacturing (100%)Processing—incorporation into article
- •Propellants, non-motive (blowing agents) in Explosives Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Polymerization promoter in Wholesale and Retail Trade (100%)Processing—repackaging
Vendor Pricing
$0.01/gAaron Chemicals LLC
CountryHong Kong
Pack$11.00 / 1 kg
Purity99.5%
Vendors22 available
Prices reflect listed pack sizes. Small research packs run far above bulk rates.
21 more vendors
| Vendor | Country Supplier country. Where available, shows shipping origin. When the supplier ships from a different country than where they are registered, both are shown. Most suppliers show registration country only. | $/g | Pack | Purity |
|---|---|---|---|---|
| Angene Chemical | China → Hong Kong | $0.01 | 1 kg | 98% |
| A2B Chem LLC | United States | $0.02 | 1 kg | 98% |
| AA BLOCKS | United States | $0.02 | 1 kg | 98% |
| Ambeed, Inc. | United States | $0.03 | 1 kg | 98% |
| Sigma-Aldrich (Rush Stock) | Germany | $0.03 | 3 kg | 99% |
| Sigma-Aldrich | Germany | $0.03 | 3 kg | 99% |
| Apollo Scientific UK | United Kingdom | $0.05 | 1 kg | — |
| AK Scientific Specialized | United States | $0.10 | 500 g | 95% |
| AK Scientific, Inc. | United States | $0.13 | 500 g | 98% |
| Combi-Blocks, Inc. | United States | $0.25 | 1 kg | 98% |
| Angene International Limited | United States | $0.28 | 500 g | 98% |
| Fluorochem EU | Germany | $0.34 | 25 g | 97% |
| AstaTech, Inc | United States | $1.16 | 25 g | 95% |
| Fluorochem UK | United Kingdom | $7.15 | 1 g | 97% |
| Labotest KG | Germany | $217.80 | 5000 mg | 90% |
| MedChemExpress MCE | Sweden | $1500.40 | 100 mg | — |
| ChemBridge Corporation | Kazakhstan | $1860.00 | 100 mg | 90% |
| Otava, Ltd. | Ukraine | $2280.00 | 50 mg | 95% |
| Otava, Ltd. (2 weeks) | Ukraine | $2724.00 | 50 mg | 90% |
| Princeton BioMolecular Research (SC) | United States | $2900.00 | 100 mg | 90% |
| Angene | China → Hong Kong | $4266.67 | 30 mg | 99.5% |
Chemical Identity
CAS461-58-5
PubChem CID10005
DTXSIDDTXSID1020354
FormulaC2H4N4
Mol. Weight84.08 g/mol
SMILESC(#N)N=C(N)N
Data Sources
- EPA CompTox (DSSTox) · DTXSID1020354Retrieved 2026-04-06
- PubChem · compound 10005Retrieved 2026-04-06
- EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
- EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
- US Census international tradeReporting year: 2024 · Retrieved 2026-10-04
Brief citations
Cyanoguanidine (CAS 461-58-5) https://chemicalindependence.com/chemical/461-58-5/ EPA CompTox (DSSTox): DTXSID1020354. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID1020354 PubChem: 10005. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/10005 EPA Chemical Data Reporting: 461-58-5. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 461-58-5. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 292620 for CAS 461-58-5. Reporting year: 2024. https://usatrade.census.gov/