1,1,1,3,3-Pentafluoropropane

CAS 460-73-1

U.S. production volumes are classified as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$14M

Top sourceChina 88%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023.

Where It Comes From

Customs basis: HS 290347 · exact

EPA reports by year

2023: US production Confidential · Imports Confidential
2019: US production Confidential · Imports Confidential

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 88%ChinaJP 10%JapanCA 1%CanadaMX 1%Mexico

Domestic parents -- activity not disclosed (1)

EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.

Honeywell International (123312)

EPA-registered importers (4)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

A-Gas

Huntsman

Icool Usa Incorporated

Wego Chemical Group

Why It Matters

Sectors

EnergyElectronicsConstructionMetals & MiningPlastics & RubberConsumer ProductsCore Chemicals

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

Used in 7 sectors as 5 functional roles.

•Foamant in Wholesale and Retail TradeProcessing—incorporation into formulation, mixture, or reaction product
•Refrigerants in Industrial Gas ManufacturingProcessing—repackaging
•Refrigerants in Electrical Equipment, Appliance, and Component ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
•Cleaning agent in Fabricated Metal Product ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
•Intermediate in All Other Basic Inorganic Chemical ManufacturingProcessing as a reactant
•Foamant in Plastics Material and Resin ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
•Propellants, non-motive (blowing agents) in Construction (100%)Processing—incorporation into formulation, mixture, or reaction product

Chemical Identity

CAS460-73-1

PubChem CID68030

DTXSIDDTXSID6052110

FormulaC3H3F5

Mol. Weight134.05 g/mol

SMILESC(C(F)F)C(F)(F)F

Data Sources

EPA CompTox (DSSTox) · DTXSID6052110Retrieved 2026-04-06
PubChem · compound 68030Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

1,1,1,3,3-Pentafluoropropane (CAS 460-73-1) https://chemicalindependence.com/chemical/460-73-1/ EPA CompTox (DSSTox): DTXSID6052110. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID6052110 PubChem: 68030. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/68030 EPA Chemical Data Reporting: 460-73-1. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 460-73-1. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 290347 for CAS 460-73-1. Reporting year: 2024. https://usatrade.census.gov/