angiotensin ii

Drug ingredient

CAS 4474-91-3

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 4474-91-3
US productionNot reported
Import value, 2024$16.4B
Top sourceIreland 94%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293719 · basket

These shares come from HS customs code 293719, which covers 53 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
IE 94%IrelandAR 4%ArgentinaCN 1%ChinaDK 1%Denmark
2 FDA-registered drug labelers
Gland Pharma Limited
La Jolla Pharmaceutical Company

Why It Matters

Sectors
Health
Downstream Uses

Appears in 2 drug and cosmetic product listings (FDA).

  • •Giapreza
  • •Angiotensin II
FDA Shortage Status
No FDA shortage records

Chemical Identity

CAS4474-91-3
PubChem CID172198
DTXSIDDTXSID30196288
FormulaC50H71N13O12
Mol. Weight1046.2 g/mol
SMILESCCC(C)C(C(=O)NC(CC1=CN=CN1)C(=O)N2CCCC2C(=O)NC(CC3=CC=CC=C3)C(=O)O)NC(=O)C(CC4=CC=C(C=C4)O)NC(=O)C(C(C)C)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC(=O)O)N

Data Sources

Brief citations

angiotensin ii (CAS 4474-91-3) https://chemicalindependence.com/chemical/4474-91-3/ PubChem: 172198. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/172198 FDA National Drug Code directory: CAS 4474-91-3. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293719 for CAS 4474-91-3. Reporting year: 2024. https://usatrade.census.gov/