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Pazopanib

Drug ingredient

CAS 444731-52-6

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 444731-52-6
US productionNot reported
Import value, 2024$2.0B
Top sourceIreland 63%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293590 · basket

These shares come from HS customs code 293590, which covers 182 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
IE 63%IrelandSG 14%SingaporeIN 7%IndiaCN 7%ChinaCH 2%Switzerland
2 FDA-registered drug labelers
Apotex Corp.
Golden State Medical Supply, Inc.

Why It Matters

Sectors
Health
Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

  • •Pazopanib
FDA Shortage Status
No FDA shortage records

Chemical Identity

CAS444731-52-6
PubChem CID10113978
DTXSIDDTXSID8048733
FormulaC21H23N7O2S
Mol. Weight437.5 g/mol
SMILESCC1=C(C=C(C=C1)NC2=NC=CC(=N2)N(C)C3=CC4=NN(C(=C4C=C3)C)C)S(=O)(=O)N

Data Sources

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Brief citations

Pazopanib (CAS 444731-52-6) https://chemicalindependence.com/chemical/444731-52-6/ PubChem: 10113978. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/10113978 FDA National Drug Code directory: CAS 444731-52-6. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293590 for CAS 444731-52-6. Reporting year: 2024. https://usatrade.census.gov/