Vandetanib

Drug ingredient

CAS 443913-73-3

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$7.6B

Top sourceIreland 61%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293359 · basket

These shares come from HS customs code 293359, which covers 295 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IE 61%IrelandCH 30%SwitzerlandGB 2%United KingdomCN 2%ChinaIN 1%India

Israel
Bulgaria
Japan
Spain
Sweden
Canada
Taiwan
Finland
Portugal
Mexico
Belgium
Hungary
Austria
Brazil
Ukraine
Croatia
Malta
South Korea
South Africa
Denmark
Czech Republic
Malaysia
Argentina
Poland
Cameroon
Australia
Hong Kong
Slovakia
Latvia

4 FDA-registered drug labelers

Catalent Micron Technologies, Inc.

Genzyme Corporation

Lonza AG

PENN PHARMACEUTICAL SERVICES LIMITED

Why It Matters

Sectors

Health

Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

•Caprelsa

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$25.20/gCombi-Blocks, Inc.

CountryUnited States

Pack$630.00 / 25 g

Purity98%

Vendors24 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

23 more vendors

Vendor	Country	$/g	Pack	Purity
Aaron Chemicals LLC	Hong Kong	$27.40	5 g	99%
BLD Pharmatech Ltd.	China	$28.80	25 g	99%
Angene Chemical	China → Hong Kong	$29.20	5 g	99%
A2B Chem LLC	United States	$30.60	25 g	99%
AK Scientific Specialized	United States	$32.00	10 g	95%
AA BLOCKS	United States	$32.28	25 g	99%
Ambeed, Inc.	United States	$44.00	5 g	99%
AstaTech, Inc	United States	$47.80	5 g	99%
BLD Pharmatech Co., Limited	United States	$75.00	1 g	99%
MedKoo Biosciences, Inc	United States	$165.00	10 g	98%
BLD Pharmatech GmbH	Germany	$248.00	250 mg	99%
Molnova	China	$716.00	500 mg	99%
TargetMol Chemicals	China → United States	$796.00	500 mg	99.99%
MedChemExpress MCE	Sweden	$1197.90	500 mg	99.95%
ChemFaces	China	$1500.00	20 mg	98%
Angene International Limited	United States	$1640.00	500 mg	98%
TargetMol Chemicals EU	Austria	$1780.00	100 mg	99.99%
Apexbio Technology LLC	United States	$2150.00	100 mg	99.63%
AK Scientific, Inc.	United States	$2150.00	100 mg	98%
Life Chemicals Inc.	Ukraine → Canada	$4200.00	50 mg	90%
Angene	China → Hong Kong	$4266.67	30 mg	99%
Cayman Europe	Estonia	$4890.90	100 mg	98%
Axon Medchem	Netherlands	$5760.00	25 mg	99%

Chemical Identity

CAS443913-73-3

PubChem CID3081361

DTXSIDDTXSID1046681

FormulaC22H24BrFN4O2

Mol. Weight475.4 g/mol

SMILESCN1CCC(CC1)COC2=C(C=C3C(=C2)N=CN=C3NC4=C(C=C(C=C4)Br)F)OC

Data Sources

PubChem · compound 3081361Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Vandetanib (CAS 443913-73-3) https://chemicalindependence.com/chemical/443913-73-3/ PubChem: 3081361. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/3081361 FDA National Drug Code directory: CAS 443913-73-3. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293359 for CAS 443913-73-3. Reporting year: 2024. https://usatrade.census.gov/