Isoleucine

Drug ingredient

CAS 443-79-8

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 443-79-8
US productionNot reported
Import value, 2024$503M
Top sourceChina 25%

This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 292249 · basket

These shares come from HS customs code 292249, which covers 170 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
CN 25%ChinaIN 17%IndiaSG 13%SingaporeIT 9%ItalyCH 7%Switzerland
15 FDA-registered drug labelers
Ajinomoto do Brasil Industria e Comercio de Alimentos Ltda.
Ajinomoto Health & Nutrition North America Inc.
B. Braun Medical Inc.
Baxter Healthcare Company
Baxter Healthcare Corporation
BioActive Nutritional, Inc.
Energique, Inc.
Fresenius Kabi USA, LLC
Guna spa
ICU Medical Inc.
KYOWA HAKKO BIO CO., LTD.
Liddell Laboratories, Inc.
Nutritional Specialties, Inc.
Shanghai Ajinomoto Amino Acid Co., Ltd.
Shanghai Plumino Amino Acid Co., Ltd.

Why It Matters

Sectors
Health
Downstream Uses

Appears in 18 drug and cosmetic product listings (FDA).

  • •Aminosyn-PF
  • •Strength F
  • •Plenamine
  • •Kabiven
  • •Clinimix
  • •Clinimix E
  • •Clinisol
  • •ProSol
FDA Shortage Status
No FDA shortage records

Vendor Pricing

$0.33/gBLD Pharmatech Ltd.
CountryChina
Pack$331.00 / 1 kg
Purity95%
Vendors16 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

Chemical Identity

CAS443-79-8
PubChem CIDNot recorded
DTXSIDDTXSID2046882
FormulaC6H13NO2
Mol. Weight131.175 g/mol
SMILESCC[C@H](C)[C@H](N)C(O)=O

Data Sources

Brief citations

Isoleucine (CAS 443-79-8) https://chemicalindependence.com/chemical/443-79-8/ EPA TSCA Inventory: CAS 443-79-8. Retrieved 2026-10-04. https://www.epa.gov/tsca-inventory FDA National Drug Code directory: CAS 443-79-8. Retrieved 2026-10-04. https://open.fda.gov/data/ndc/ US Census international trade: HS 292249 for CAS 443-79-8. Reporting year: 2024. https://usatrade.census.gov/