trifluoperazine hydrochloride

Drug ingredient

CAS 440-17-5

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$13M

Top sourceGermany 54%

This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293430 · basket

These shares come from HS customs code 293430, which covers 19 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

DE 54%GermanyIT 24%ItalyIN 8%IndiaCN 5%ChinaZA 4%South Africa

Canada
Switzerland
United Kingdom

6 FDA-registered drug labelers

Bryant Ranch Prepack

Mylan Institutional Inc.

Mylan Pharmaceuticals Inc.

REMEDYREPACK INC.

Sandoz Inc.

Trifluoperazine Hydrochloride

Why It Matters

Sectors

Health

Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

•Trifluoperazine Hydrochloride

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$6.74/gAaron Chemicals LLC

CountryHong Kong

Pack$674.00 / 100 g

Purity98%

Vendors23 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

22 more vendors

Vendor	Country	$/g	Pack	Purity
Angene Chemical	China → Hong Kong	$6.79	100 g	98%
A2B Chem LLC	United States	$7.40	25 g	98%
Combi-Blocks, Inc.	United States	$7.40	25 g	95%
AK Scientific Specialized	United States	$7.44	25 g	95%
AA BLOCKS	United States	$10.09	100 g	98%
Cayman Europe	Estonia	$12.00	25 g	98%
AK Scientific, Inc.	United States	$13.60	25 g	98%
Angene International Limited	United States	$22.28	25 g	98%
Sigma-Aldrich (Rush Stock)	Germany	$23.61	5 g	99%
Sigma-Aldrich	Germany	$23.61	5 g	99%
MedKoo Biosciences, Inc	United States	$43.00	10 g	98%
Apexbio Technology LLC	United States	$170.00	500 mg	99.22%
MedChemExpress MCE	Sweden	$210.54	500 mg	99.98%
Interbioscreen	Hong Kong	$238.00	10 g	95%
AstaTech (2 weeks)	United States	$314.80	5 g	98%
Molnova	China	$450.00	100 mg	99%
Fulfilled by Molport	Latvia	$1200.00	15 mg	99%
Princeton BioMolecular Research (SC)	United States	$2900.00	100 mg	90%
Vitas M Chemical Limited	Hong Kong	$3170.00	100 mg	90%
Angene	China → Hong Kong	$4266.67	30 mg	98%
Key Organics Ltd.	United Kingdom	$6900.00	10 mg	97%
TimTec, LLC	United States	$14666.67	30 mg	90%

Chemical Identity

CAS440-17-5

PubChem CID66064

DTXSIDDTXSID1045085

FormulaC21H26Cl2F3N3S

Mol. Weight480.4 g/mol

SMILESCN1CCN(CC1)CCCN2C3=CC=CC=C3SC4=C2C=C(C=C4)C(F)(F)F.Cl.Cl

Data Sources

PubChem · compound 66064Retrieved 2026-04-07
EPA TSCA InventoryRetrieved 2026-04-24
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

trifluoperazine hydrochloride (CAS 440-17-5) https://chemicalindependence.com/chemical/440-17-5/ PubChem: 66064. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/66064 EPA TSCA Inventory: CAS 440-17-5. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293430 for CAS 440-17-5. Reporting year: 2024. https://usatrade.census.gov/