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Diazepam

Drug ingredient

CAS 439-14-5

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 439-14-5
US productionNot reported
Import value, 2024$10M
Top sourceItaly 73%

This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293391 · basket

These shares come from HS customs code 293391, which covers 14 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
IT 73%ItalyIN 21%IndiaIL 4%IsraelFI 1%Finland
52 FDA-registered drug labelers
A-S Medication Solutions
Advanced Rx of Tennessee, LLC
Advanced Rx Pharmacy of Tennessee, LLC
Alembic Pharmaceuticals Inc.
Alembic Pharmaceuticals Limited
American Health Packaging
Aphena Pharma Solutions - Tennessee, LLC
Apothecon Pharmaceuticals Pvt Ltd
ASCLEMED USA INC.
Aurobindo Pharma Limited
Bryant Ranch Prepack
Cambrex Profarmaco Milano Srl
Cardinal Health 107, LLC
Catalent Pharma Solutions, LLC
Centaur Pharmaceuticals Private Limited
Chartwell Governmental & Specialty RX, LLC.
Chartwell RX, LLC
Civica, Inc.
Clinical Solutions Wholesale, LLC
Direct_Rx
Dr. Reddy's Laboratories Inc
F.I.S. FABBRICA ITALIANA SINTETICI S.P.A.
Fagron Inc
Fresenius Kabi USA, LLC
Henry Schein, Inc.
Hikma Pharmaceuticals USA Inc.
Hospira, Inc.
Lupin Pharmaceuticals,Inc.
Medical Purchasing Solutions, LLC
Medisca Inc.
Meridian Medical Technologies LLC
Mylan Institutional Inc.
Mylan Pharmaceuticals Inc.
Natco Pharma USA LLC
Navinta LLC
Neurelis, Inc
NuCare Pharmaceuticals, Inc
Oceanside Pharmaceuticals
PD-Rx Pharmaceuticals, Inc.
Pharmaceutical Associates, Inc.
Precision Dose Inc.
Preferred Pharmaceuticals Inc.
Professional Compounding Centers of America
Proficient Rx LP
R.L.Fine Chem Private Limited
REMEDYREPACK INC.
Roche Laboratories Inc.
Safecor Health, LLC
Sagent Pharmaceuticals
Sunrise Pharmaceutical, Inc.
Teva Pharmaceuticals USA, Inc.
Zydus Pharmaceuticals USA Inc.

Why It Matters

Sectors
Health
Downstream Uses

Appears in 4 drug and cosmetic product listings (FDA).

  • •Diazepam Intensol
  • •Diazepam
  • •Valtoco
  • •Valium
FDA Shortage Status
No FDA shortage records

Chemical Identity

CAS439-14-5
PubChem CID3016
DTXSIDDTXSID4020406
FormulaC16H13ClN2O
Mol. Weight284.74 g/mol
SMILESCN1C(=O)CN=C(C2=C1C=CC(=C2)Cl)C3=CC=CC=C3

Data Sources

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Brief citations

Diazepam (CAS 439-14-5) https://chemicalindependence.com/chemical/439-14-5/ PubChem: 3016. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/3016 EPA TSCA Inventory: CAS 439-14-5. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293391 for CAS 439-14-5. Reporting year: 2024. https://usatrade.census.gov/