lutetium oxodotreotide lu-177

Drug ingredient

CAS 437608-50-9

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 437608-50-9 — 1 Lu³⁺

US productionNot reported

Import value, 2024$941M

Top sourceCanada 61%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 284443 · basket

These shares come from HS customs code 284443, which covers 14 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CA 61%CanadaNL 12%NetherlandsDE 8%GermanyIT 7%ItalyBE 3%Belgium

Australia
Finland
United Kingdom
Norway
Uzbekistan
Switzerland
Israel
Brazil
Poland
Kazakhstan
Libya
Japan
China
Denmark
Spain
Hungary
United Arab Emirates
Singapore
Oman
Colombia

1 FDA-registered drug labeler

Advanced Accelerator Applications USA, Inc

Why It Matters

Sectors

Health

Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

•Lutathera

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Chemical Identity

CAS437608-50-9

PubChem CID76966897

DTXSIDDTXSID20195927

FormulaC65H87LuN14O19S2

Mol. Weight1609.5 g/mol

SMILESCC(C1C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCCN)CC2=CNC3=CC=CC=C32)CC4=CC=C(C=C4)O)NC(=O)C(CC5=CC=CC=C5)NC(=O)CN6CCN(CCN(CCN(CC6)CC(=O)[O-])CC(=O)[O-])CC(=O)[O-])C(=O)NC(C(C)O)C(=O)O)O.[Lu+3]

Data Sources

PubChem · compound 76966897Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

lutetium oxodotreotide lu-177 (CAS 437608-50-9) https://chemicalindependence.com/chemical/437608-50-9/ PubChem: 76966897. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/76966897 FDA National Drug Code directory: CAS 437608-50-9. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 284443 for CAS 437608-50-9. Reporting year: 2024. https://usatrade.census.gov/