Perfluoro(methyloxirane)

CAS 428-59-1

U.S. production volumes are classified as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$87M

Top sourceChina 27%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 291090 · basket

EPA reports by year

2023: US production Confidential · Imports Confidential
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 291090, which covers 69 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 27%ChinaJP 26%JapanIT 15%ItalyDE 6%GermanyIN 5%India

Ukraine
Singapore
Canada
Finland
Belgium
Spain

EPA-registered manufacturers (1)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Domestic parents -- activity not disclosed (1)

EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.

Chemours

Why It Matters

Sectors

Core Chemicals

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

•Intermediate in All Other Basic Organic Chemical ManufacturingProcessing as a reactant

Vendor Pricing

$6.24/gAaron Chemicals LLC

CountryHong Kong

Pack$156.00 / 25 g

Purity95%

Vendors6 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

5 more vendors

Vendor	Country	$/g	Pack	Purity
Angene Chemical	China → Hong Kong	$6.72	25 g	95%
AstaTech (2 weeks)	United States	$12.80	25 g	95%
A2B Chem LLC	United States	$15.60	5 g	—
AA BLOCKS	United States	$20.00	5 g	—
Angene	China → Hong Kong	$4266.67	30 mg	95%

Chemical Identity

CAS428-59-1

PubChem CID9883

DTXSIDDTXSID6029177

FormulaC3F6O

Mol. Weight166.02 g/mol

SMILESC1(C(O1)(F)F)(C(F)(F)F)F

Data Sources

EPA CompTox (DSSTox) · DTXSID6029177Retrieved 2026-04-06
PubChem · compound 9883Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Perfluoro(methyloxirane) (CAS 428-59-1) https://chemicalindependence.com/chemical/428-59-1/ EPA CompTox (DSSTox): DTXSID6029177. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID6029177 PubChem: 9883. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/9883 EPA Chemical Data Reporting: 428-59-1. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 428-59-1. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 291090 for CAS 428-59-1. Reporting year: 2024. https://usatrade.census.gov/