N-tert-Octylacrylamide

CAS 4223-03-4

U.S. production volumes are classified as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$371M

Top sourceChina 27%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 292419 · basket

EPA reports by year

2023: US production Confidential · Imports Confidential
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 292419, which covers 211 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 27%ChinaIN 18%IndiaDE 14%GermanyIT 10%ItalyGB 6%United Kingdom

Hungary
Austria
Spain
Egypt
Canada
Sweden
Ukraine
Denmark
Israel
Lithuania
Greece
Ireland
Taiwan
Uruguay
Turkey
Australia
Singapore
Latvia
Colombia

Why It Matters

Sectors

EnergyCore Chemicals

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

Used in 3 sectors as 2 functional roles.

•Intermediate in All Other Basic Organic Chemical Manufacturing (10%)Processing as a reactant
•Intermediate in All Other Chemical Product and Preparation Manufacturing (20%)Processing as a reactant
•Lubricating agent in All Other Chemical Product and Preparation Manufacturing (1%)Processing as a reactant
•Lubricating agent in Petroleum Lubricating Oil and Grease Manufacturing (70%)Use—non-incorporative activities

Vendor Pricing

$0.44/gAaron Chemicals LLC

CountryHong Kong

Pack$442.00 / 1 kg

Purity98%

Vendors8 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

7 more vendors

Vendor	Country	$/g	Pack	Purity
Angene Chemical	China → Hong Kong	$0.50	500 g	98%
AA BLOCKS	United States	$0.80	100 g	98%
Combi-Blocks, Inc.	United States	$0.86	500 g	95%
A2B Chem LLC	United States	$0.92	500 g	98%
AK Scientific, Inc.	United States	$1.64	25 g	95%
Angene International Limited	United States	$3.96	25 g	95%
Angene	China → Hong Kong	$4266.67	30 mg	98%

Chemical Identity

CAS4223-03-4

PubChem CID171970

DTXSIDDTXSID5027564

FormulaC11H21NO

Mol. Weight183.29 g/mol

SMILESCC(C)(C)CC(C)(C)NC(=O)C=C

Data Sources

EPA CompTox (DSSTox) · DTXSID5027564Retrieved 2026-04-06
PubChem · compound 171970Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2019 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

N-tert-Octylacrylamide (CAS 4223-03-4) https://chemicalindependence.com/chemical/4223-03-4/ EPA CompTox (DSSTox): DTXSID5027564. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID5027564 PubChem: 171970. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/171970 EPA Chemical Data Reporting: 4223-03-4. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 4223-03-4. Reporting year: 2019. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 292419 for CAS 4223-03-4. Reporting year: 2024. https://usatrade.census.gov/