Clonidine

Drug ingredient

CAS 4205-90-7

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$114M

Top sourceChina 26%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293329 · basket

These shares come from HS customs code 293329, which covers 173 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 26%ChinaIN 17%IndiaKR 16%South KoreaDE 9%GermanyIT 9%Italy

Australia
Brazil
Czech Republic
Ireland
Sweden
Ukraine
Poland
United Arab Emirates
Hungary
Israel
Netherlands
Canada
Saudi Arabia
Greece
Belgium
Austria
Latvia
Singapore
Denmark

13 FDA-registered drug labelers

Actavis Pharma, Inc.

Alembic Pharmaceuticals Limited

Athena Bioscience, LLC

Catalent Micron Technologies, Inc.

Dr. Reddy's Labratories Inc.

Mayne Pharma Inc.

Mylan Pharmaceuticals Inc.

PALMETTO PHARMACEUTICALS INC.

PCAS FINLAND OY

Societa Italiana Medicinali Scandicci S.I.M.S., SrL

Technomed Inc.

TruPharma, LLC

Zydus Lifesciences Limited

Why It Matters

Sectors

Health

Downstream Uses

Appears in 9 drug and cosmetic product listings (FDA).

•Clonidine transdermal system
•Catapres-TTS-1
•Catapres-TTS-3
•Clonidine
•Catapres-TTS-2
•Nexiclon XR
•Clonidine Transdermal System USP, 0.2 mg/day
•Clonidine Transdermal System USP, 0.3 mg/day

Show all 9

•Clonidine Transdermal System USP, 0.1 mg/day

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$204.80/gAaron Chemicals LLC

CountryHong Kong

Pack$1024.00 / 5 g

Purity98%

Vendors12 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

11 more vendors

Vendor	Country	$/g	Pack	Purity
Angene Chemical	China → Hong Kong	$218.80	5 g	98%
A2B Chem LLC	United States	$570.00	500 mg	99.44%
TargetMol Chemicals	China → United States	$646.00	500 mg	99.88%
AA BLOCKS	United States	$744.00	500 mg	98%
Molnova	China	$1190.00	100 mg	99%
MedKoo Biosciences, Inc	United States	$1250.00	1 g	98%
TargetMol Chemicals EU	Austria	$1320.00	100 mg	99.88%
MedChemExpress MCE	Sweden	$1996.50	100 mg	99.96%
Angene International Limited	United States	$3310.00	100 mg	98%
Princeton BioMolecular Research (SC)	United States	$6500.00	20 mg	90%
TimTec, LLC	United States	$32000.00	10 mg	90%

Chemical Identity

CAS4205-90-7

PubChem CID2803

DTXSIDDTXSID6022846

FormulaC9H9Cl2N3

Mol. Weight230.09 g/mol

SMILESC1CN=C(N1)NC2=C(C=CC=C2Cl)Cl

Data Sources

PubChem · compound 2803Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Clonidine (CAS 4205-90-7) https://chemicalindependence.com/chemical/4205-90-7/ PubChem: 2803. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/2803 FDA National Drug Code directory: CAS 4205-90-7. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293329 for CAS 4205-90-7. Reporting year: 2024. https://usatrade.census.gov/