C.I. Fluorescent Brightener 28, disodium salt

CAS 4193-55-9

U.S. production volumes are classified as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$44M

Top sourceIndia 28%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 320420 · basket

EPA reports by year

2023: US production Confidential · Imports Confidential
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 320420, which covers 16 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IN 28%IndiaCH 26%SwitzerlandTW 22%TaiwanDE 9%GermanyCN 8%China

Indonesia
Italy
Lithuania
Czech Republic
Canada
Sweden
Singapore
Japan
Hong Kong
Netherlands
Hungary
Armenia
Guatemala

EPA-registered manufacturers (2)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Archroma Management Gmbh · CH Switzerland

Archroma U.S

Domestic parents -- activity not disclosed (1)

EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.

Milliken &

EPA-registered importers (1)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Tfm North America

Why It Matters

Sectors

TextilesPaper & Printing

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

Used in 2 sectors as 2 functional roles.

•Brightener in Paper ManufacturingProcessing—repackaging
•Dye in Synthetic Dye and Pigment Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product

Chemical Identity

CAS4193-55-9

PubChem CID6108780

DTXSIDDTXSID9044669

FormulaC40H44N12O10S2

Mol. Weight917 g/mol

SMILESC1=CC=C(C=C1)NC2=NC(=NC(=N2)N(CCO)CCO)NC3=CC(=C(C=C3)C=CC4=C(C=C(C=C4)NC5=NC(=NC(=N5)NC6=CC=CC=C6)N(CCO)CCO)S(=O)(=O)O)S(=O)(=O)O

Data Sources

EPA CompTox (DSSTox) · DTXSID9044669Retrieved 2026-04-06
PubChem · compound 6108780Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

C.I. Fluorescent Brightener 28, disodium salt (CAS 4193-55-9) https://chemicalindependence.com/chemical/4193-55-9/ EPA CompTox (DSSTox): DTXSID9044669. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID9044669 PubChem: 6108780. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/6108780 EPA Chemical Data Reporting: 4193-55-9. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 4193-55-9. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 320420 for CAS 4193-55-9. Reporting year: 2024. https://usatrade.census.gov/