Apomorphine hydrochloride

Drug ingredient

CAS 41372-20-7

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 41372-20-7 — 2 HCl · 1 H₂O

US productionNot reported

Import value, 2024$1.4B

Top sourceIreland 33%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293399 · basket

These shares come from HS customs code 293399, which covers 518 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IE 33%IrelandCN 26%ChinaIN 11%IndiaDE 9%GermanyIT 4%Italy

Taiwan
Poland
Canada
Ivory Coast
Greece
Hungary
Indonesia
Latvia
Belgium
Slovakia
Czech Republic
Austria
Netherlands
Finland
Denmark
Croatia
Australia
South Africa
Sweden
Hong Kong
Malta
Singapore
Lithuania
Malaysia
Oman
Serbia

16 FDA-registered drug labelers

Cutyx Research LLP

DNA Labs, Inc.

FRANCOPIA

Guna spa

LETCO MEDICAL, LLC

MACFARLAN SMITH LIMITED

MDD US Operations, LLC

MDD US Operations, LLC, a subsidiary of Supernus Pharmaceuticals, Inc

Medisca Inc.

Patheon Italia S.p.A.

Professional Complementary Health Formulas

Professional Compounding Centers of America dba PCCA

Rusan Pharma Ltd

Sanofi Winthrop Industrie

Spectrum Laboratory Products, Inc.

TruPharma, LLC

Why It Matters

Sectors

Health

Downstream Uses

Appears in 6 drug and cosmetic product listings (FDA).

•GUNA-Reflux
•Apokyn
•D-52
•Travel Sickness Drops 2075
•apomorphine hydrocloride
•Onapgo

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Chemical Identity

CAS41372-20-7

PubChem CID107882

DTXSIDDTXSID0048185

FormulaC34H38Cl2N2O5

Mol. Weight625.6 g/mol

SMILESCN1CCC2=C3C1CC4=C(C3=CC=C2)C(=C(C=C4)O)O.CN1CCC2=C3C1CC4=C(C3=CC=C2)C(=C(C=C4)O)O.O.Cl.Cl

Data Sources

PubChem · compound 107882Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Apomorphine hydrochloride (CAS 41372-20-7) https://chemicalindependence.com/chemical/41372-20-7/ PubChem: 107882. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/107882 FDA National Drug Code directory: CAS 41372-20-7. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293399 for CAS 41372-20-7. Reporting year: 2024. https://usatrade.census.gov/