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memantine hydrochloride

Drug ingredient

CAS 41100-52-1

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 41100-52-1
1 HCl
US productionNot reported
Import value, 2024$56M
Top sourceCzech Republic 24%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 292130 · basket

These shares come from HS customs code 292130, which covers 39 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
CZ 24%Czech RepublicBE 18%BelgiumDE 17%GermanyCN 16%ChinaCA 4%Canada
64 FDA-registered drug labelers
A-S Medication Solutions
Actavis Pharma, Inc.
Ajanta Pharma USA Inc.
Alembic Pharmaceuticals Inc.
Alembic Pharmaceuticals Limited
Allergan, Inc.
American Health Packaging
Amneal Pharmaceuticals LLC
Amneal Pharmaceuticals NY LLC
Amneal Pharmaceuticals of New York LLC
ANI Pharmaceuticals, Inc.
Anonima Materie Sintetiche and Affini (AMSA) Spa
Aphena Pharma Solutions - Tennessee, LLC
Apotex Corp.
Apotex Inc.
Aurobindo Pharma Limited
AvKARE
AvPAK
Bryant Ranch Prepack
Camber Pharmaceuticals, Inc.
Cardinal Health 107, LLC
Carlsbad Technology, Inc.
Chartwell Governmental & Specialty RX, LLC.
Chartwell RX, LLC
Chemo Biosynthesis s.r.l.
Cohance Lifesciences Limited
Coupler LLC
DirectRx
Dr. Reddys Laboratories Limited
Emcure Pharmaceuticals Limited
Hainan Poly Pharm. Co., Ltd.
Hetero Drugs Limited
HIKAL LIMITED
Industriale Chimica s.r.l.
Lundbeck Pharmaceuticals Italy S.p.A.
Lupin Pharmaceuticals, Inc.
Macleods Pharmaceuticals Limited
Major Pharmaceuticals
Matrix Pharmacorp Private Limited
Megafine Pharma (P) Limited
MSN Pharmachem Private Limited
NCS HealthCare of KY, LLC dba Vangard Labs
NorthStar RxLLC
Olon SpA
Olpha AS
Optimus Drugs Private Limited
POLYGEN PHARMACEUTICALS INC.
Preferred Pharmaceuticals Inc.
PROCOS S.p.A.
REMEDYREPACK INC.
Rising Pharma Holdings, Inc.
Seton Pharmaceuticals
SICOR Societa' Italiana Corticosteroidi s.r.l.
Siegfried Evionnaz SA
Slate Run Pharmaceuticals, LLC
Sun Pharmaceutical Industries, Inc.
Unichem Laboratories Limited, India
Unichem Pharmaceuticals (USA), Inc.
Upsher-Smith Laboratories, LLC
Uquifa Spain
Viona Pharmaceuticals Inc
Vitruvias Therapeutics, Inc.
Zydus Lifesciences Limited
Zydus Pharmaceuticals USA Inc.

Why It Matters

Sectors
Health
Downstream Uses

Appears in 8 drug and cosmetic product listings (FDA).

  • •Memantine Hydrochloride
  • •Memantine
  • •Memantine and Donepezil
  • •Memantine and Donepezil Hydrochlorides Extended-release
  • •memantine hydrochloride and donepezil hydrochloride
  • •Namzaric
  • •Memantine AND Donepezil Hydrochlorides
  • •Memantine HCL
FDA Shortage Status
No Shortage

Chemical Identity

CAS41100-52-1
PubChem CID181458
DTXSIDDTXSID90961439
FormulaC12H22ClN
Mol. Weight215.76 g/mol
SMILESCC12CC3CC(C1)(CC(C3)(C2)N)C.Cl

Data Sources

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Brief citations

memantine hydrochloride (CAS 41100-52-1) https://chemicalindependence.com/chemical/41100-52-1/ PubChem: 181458. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/181458 FDA National Drug Code directory: CAS 41100-52-1. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA Drug Shortages: CAS 41100-52-1. Retrieved 2026-06-13. https://www.accessdata.fda.gov/scripts/drugshortages/ US Census international trade: HS 292130 for CAS 41100-52-1. Reporting year: 2024. https://usatrade.census.gov/