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p-Toluenesulphonyl isocyanate

CAS 4083-64-1

Used in 4 industrial sectors tracked by the EPA.

Molecular structure of 4083-64-1
US production1.5M lb
Import value, 2024$2.0B
Import volumeCBI
Top sourceIreland 63%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293590 · basket

EPA reports by year
2023
US production 1.5M lb · Imports Confidential
2019
US production Confidential · Imports Confidential

These shares come from HS customs code 293590, which covers 182 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
IE 63%IrelandSG 14%SingaporeIN 7%IndiaCN 7%ChinaCH 2%Switzerland
EPA-registered manufacturers (1)
Vandemark Chemical
EPA-registered importers (4)
Mercedes-Benz Ag · DE Germany
Aceto Us
Fci
Mercedes Benz U.S

Why It Matters

Sectors
TransportationConstructionPlastics & RubberPaints & Coatings
Downstream UsesNot recorded
FDA Shortage Status
No FDA shortage records

Industrial Uses

Used in 4 sectors as 3 functional roles.

  • •Adhesion/cohesion promoter in Asphalt Paving, Roofing, and Coating Materials Manufacturing (100%)Processing as a reactant
  • •Intermediate in Paint and Coating Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
  • •Dehydrating agent (desiccant) in Asphalt Paving, Roofing, and Coating Materials Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
  • •Dehydrating agent (desiccant) in Plastics Material and Resin Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
  • •Adhesion/cohesion promoter in Transportation Equipment Manufacturing (100%)Processing—incorporation into article

Vendor Pricing

$0.04/gAaron Chemicals LLC
CountryHong Kong
Pack$20.00 / 500 g
Purity99%
Vendors19 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

18 more vendors
VendorCountry$/gPackPurity
Manchester OrganicsUnited Kingdom$0.041 kg—
Angene ChemicalChina → Hong Kong$0.041 kg97%
Fluorochem EUGermany$0.09500 g95%
A2B Chem LLCUnited States$0.10500 g97%
AA BLOCKSUnited States$0.13500 g97%
ChemsceneUnited States$0.15500 g—
Sigma-Aldrich (Rush Stock)Germany$0.28500 g96%
Sigma-AldrichGermany$0.28500 g96%
AstaTech, IncUnited States$0.30250 g95%
AK Scientific, Inc.United States$0.47100 g95%
Ambeed, Inc.United States$0.50100 g98%
Angene International LimitedUnited States$1.25100 g95%
InterbioscreenHong Kong$68.0010 g95%
Labotest KGGermany$453.001000 mg90%
Key Organics Ltd.United Kingdom$1960.00100 mg95%
Otava, Ltd.Ukraine$2280.0050 mg95%
Otava, Ltd. (2 weeks)Ukraine$2724.0050 mg95%
AngeneChina → Hong Kong$4266.6730 mg97%

Chemical Identity

CAS4083-64-1
PubChem CID77703
DTXSIDDTXSID1027558
FormulaC8H7NO3S
Mol. Weight197.21 g/mol
SMILESCC1=CC=C(C=C1)S(=O)(=O)N=C=O

Data Sources

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Brief citations

p-Toluenesulphonyl isocyanate (CAS 4083-64-1) https://chemicalindependence.com/chemical/4083-64-1/ EPA CompTox (DSSTox): DTXSID1027558. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID1027558 PubChem: 77703. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/77703 EPA Chemical Data Reporting: 4083-64-1. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 4083-64-1. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 293590 for CAS 4083-64-1. Reporting year: 2024. https://usatrade.census.gov/