(1H,1H-Perfluoroethyl)(2H-perfluoroethyl)ether

CAS 406-78-0

U.S. production volumes are classified as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$117M

Top sourceIndia 29%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 290919 · basket

EPA reports by year

2023: US production Confidential · Imports Confidential
2019: US production Zero · Imports 103.0K lb

These shares come from HS customs code 290919, which covers 93 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IN 29%IndiaCN 25%ChinaJP 20%JapanBR 6%BrazilDE 4%Germany

South Korea
Singapore
Spain
United Arab Emirates
Netherlands
Belgium
Indonesia
Poland
Mexico
Taiwan
Slovakia

Why It Matters

Sectors

Core Chemicals

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

Used in 1 sector as 2 functional roles.

•Cleaning agent in All Other Chemical Product and Preparation ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
•Solvent in All Other Chemical Product and Preparation ManufacturingProcessing—incorporation into formulation, mixture, or reaction product

Vendor Pricing

$1.43/gAstaTech, Inc

CountryUnited States

Pack$143.00 / 100 g

Purity95%

Vendors2 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

1 more vendor

Vendor	Country	$/g	Pack	Purity
Apollo Scientific US	United Kingdom	$1.61	100 g	97%

Chemical Identity

CAS406-78-0

PubChem CID164596

DTXSIDDTXSID8074786

FormulaC4H3F7O

Mol. Weight200.05 g/mol

SMILESC(C(F)(F)F)OC(C(F)F)(F)F

Data Sources

EPA CompTox (DSSTox) · DTXSID8074786Retrieved 2026-04-06
PubChem · compound 164596Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

(1H,1H-Perfluoroethyl)(2H-perfluoroethyl)ether (CAS 406-78-0) https://chemicalindependence.com/chemical/406-78-0/ EPA CompTox (DSSTox): DTXSID8074786. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID8074786 PubChem: 164596. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/164596 EPA Chemical Data Reporting: 406-78-0. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 406-78-0. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 290919 for CAS 406-78-0. Reporting year: 2024. https://usatrade.census.gov/