1,1,1,3,3-Pentafluorobutane

CAS 406-58-6

U.S. production volumes are classified as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$9M

Top sourceJapan 100%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023.

Where It Comes From

Customs basis: HS 290348 · exact

EPA reports by year

2023: US production Confidential · Imports Confidential
2019: US production Confidential · Imports Confidential

Source Countries

Country of origin for US imports, from Census customs data (2024).

JP 100%Japan

EPA-registered importers (1)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

A-Gas

Why It Matters

Sectors

Core Chemicals

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

•Foamant in All Other Basic Organic Chemical Manufacturing (0%)Processing as a reactant

Chemical Identity

CAS406-58-6

PubChem CID67884

DTXSIDDTXSID5073901

FormulaC4H5F5

Mol. Weight148.07 g/mol

SMILESCC(CC(F)(F)F)(F)F

Data Sources

EPA CompTox (DSSTox) · DTXSID5073901Retrieved 2026-04-06
PubChem · compound 67884Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

1,1,1,3,3-Pentafluorobutane (CAS 406-58-6) https://chemicalindependence.com/chemical/406-58-6/ EPA CompTox (DSSTox): DTXSID5073901. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID5073901 PubChem: 67884. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/67884 EPA Chemical Data Reporting: 406-58-6. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 406-58-6. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 290348 for CAS 406-58-6. Reporting year: 2024. https://usatrade.census.gov/