Capsaicin

Drug ingredient

CAS 404-86-4

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 404-86-4
US productionNot reported
Import value, 2024$171M
Top sourceSwitzerland 40%

This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293979 · basket

These shares come from HS customs code 293979, which covers 60 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
CH 40%SwitzerlandCN 18%ChinaIT 14%ItalyDE 13%GermanyIN 10%India
116 FDA-registered drug labelers
1ST MEDX LLC
A-S Medication Solutions
A2A Integrated Pharmaceuticals, LLC
ACA MANAGEMENT LLC
Advanced Rx of Tennessee, LLC
Advanced Rx Pharmacy of Tennessee, LLC
AHC VENTURES CORP DBA CRY
ALAINA HEALTHCARE PRIVATE LIMITED
Alexso, Inc
Allure Labs
Alps Pharmaceutical Ind. Co., Ltd.
Amerisource Bergen
ARI BRANDS, LLC
Asclemed USA, Inc.
AvPAK
Belmora LLC
Biological M.D. Solutions LLC
BIOSAVIA USA, LLC
BLUE SPRING WELLNESS, L.L.C.
Borden Company (Private) Limited
BRONSON NUTRITIONALS, LLC
Cardinal Health 110 dba LEADER
Chattem, Inc.
Chorda Pharma, Inc
Clarion Brands LLC
Clinic Pharma
CVS
CVS PHARMACY
CVS Pharmacy, Inc.
DANOUS LAND FLOOW LLC
Derma Care Research Labs, LLC
Dersan Pharmaceutical Co., Ltd
Direct_Rx
DLC Laboratories, Inc.
Eagle Indo Pharma, PT
Eagle Labs Inc
Easment LLC
Formosa Laboratories, Inc.
Foshan Aqua Gel Biotech Co.,Ltd.
FOURSTAR GROUP USA, INC.
Fullstack Fulfillment
Guchutang Biotechnology (Longyan) Co., Ltd
Haleon US Holdings LLC
HCD Sales
Henan Enokon Medical Instrument Co., Ltd.
Hmong 21
I SHAY COSMETICS INC
IDEAZ, LLC
Implus Footcare, LLC
Ion Pharma, LLC
Kareway Product, Inc.
Key 2 Health, Inc.
L'Bris, Pure 'N Natural
LTS Lohmann Therapie-Systeme AG
MADISON ONE ACME INC
Marcella Health
Medcore LLC
Meijer Distribution
Meijer Distribution Inc
Menthol pain relief patch
Milo Rod Import & Export, Inc.
Nationwide Pharmaceutical LLC
New World Imports, Inc
Nnodum Pharmaceuticals
Noble OTC LLC
NuCare Pharmaceuticals,Inc.
Nufabrx LLC
OL PHARMA TECH,LLC
PHARMACURE LLC
Pharmadel LLC
PHOENIX RX LLC
Physicians Science & Nature Inc.
Preferred Pharmaceuticals Inc.
Professional Compounding Centers of America dba PCCA
Proficient Rx LP
Proper Buys LLC
Proximity Capital Partners LLC dba Asutra
PT ELITE PRODUCTS LLC
Puretek Corporation
Puretekcorp
Rite Aid
Rugby Laboratories
SA3, LLC
Sato Pharmaceutical Co., Ltd.
Sato Pharmaceuticals Co., Ltd.
SERENU, INC.
Shanghai Chuangshi Medical Technology (Group) Co., Ltd.
Sola Pharmaceuticals
Sombra Cosmetics Inc.
Spectrum Chemicals and Laboratory Products
Strand Health Group
Tai Guk Pharm. Co., Ltd.
The Hygenic Company, LLC
The Mentholatum Company
Toprail Chp Llc.
Trifecta Pharmaceuticals USA LLC
Ubu/Elements, Inc.
Unifirst First Aid Corporation
United Exchange Corp.
United Exchange Corporation
Universal Distribution Center LLC
V2 Pharma LLC
Veridian Healthcare
Village Pharma LLC
ViolaCare, Inc.
VIRUPAKSHA ORGANICS LIMITED
VITA SCIENCES, LLC
Wal-Mart Stores Inc
Walgreen Co.
Walgreen Company
Walgreens Co
WHY ENTERPRISES LLC
Xenex Laboratories Inc.
Xuzhou Lanting Pharmaceutical Co., Ltd
YUNNAN BAIYAO GROUP CO., LTD.
ZENSEZONE LLC

Why It Matters

Sectors
Health
Downstream Uses

Appears in 139 drug and cosmetic product listings (FDA).

  • •Capsaicin Cream 0.075%
  • •Arth RX Topical Analgesic
  • •Capsaicin
  • •Toast Screamin Hot
  • •Pain Relief
  • •WellPatch Warming Pain Relief
  • •Overtime
  • •Dendracin Neurodendraxcin
FDA Shortage Status
No FDA shortage records

Vendor Pricing

$7.63/gAA BLOCKS
CountryUnited States
Pack$763.00 / 100 g
Purity95%
Vendors4 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

Chemical Identity

CAS404-86-4
PubChem CID1548943
DTXSIDDTXSID9020241
FormulaC18H27NO3
Mol. Weight305.4 g/mol
SMILESCC(C)C=CCCCCC(=O)NCC1=CC(=C(C=C1)O)OC

Data Sources

Brief citations

Capsaicin (CAS 404-86-4) https://chemicalindependence.com/chemical/404-86-4/ PubChem: 1548943. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/1548943 EPA TSCA Inventory: CAS 404-86-4. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293979 for CAS 404-86-4. Reporting year: 2024. https://usatrade.census.gov/