Trimethylsilyl trifluoroacetate

CAS 400-53-3

Acetic acid, 2,2,2-trifluoro-, trimethylsilyl ester

Molecular structure of 400-53-3
US productionNot reported
Import value, 2024$537M
Top sourceChina 39%

This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293190 · basket

These shares come from HS customs code 293190, which covers 378 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
CN 39%ChinaDE 17%GermanyIT 9%ItalyIN 7%IndiaJP 7%Japan

Why It Matters

No EPA sector or FDA product records name a use for this chemical.

Vendor Pricing

$1.51/gA2B Chem LLC
CountryUnited States
Pack$151.00 / 100 g
Purity95%
Vendors10 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

Chemical Identity

CAS400-53-3
PubChem CIDNot recorded
DTXSIDDTXSID6059944
FormulaC5H9F3O2Si
Mol. Weight186.205 g/mol
SMILESC[Si](C)(C)OC(=O)C(F)(F)F

Data Sources

Brief citations

Trimethylsilyl trifluoroacetate (CAS 400-53-3) https://chemicalindependence.com/chemical/400-53-3/ EPA TSCA Inventory: CAS 400-53-3. Retrieved 2026-10-04. https://www.epa.gov/tsca-inventory US Census international trade: HS 293190 for CAS 400-53-3. Reporting year: 2024. https://usatrade.census.gov/