Fluticasone furoate

Drug ingredient

CAS 397864-44-7

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$1.1B

Top sourceSingapore 82%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293722 · basket

These shares come from HS customs code 293722, which covers 36 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

SG 82%SingaporeGB 15%United KingdomIT 2%Italy

India
Portugal
China
Mexico
Spain
Malaysia
Canada
Israel
Jordan
Belgium

19 FDA-registered drug labelers

A-S Medication Solutions

Aarti Pharmalabs Limited

Aurisco Pharmaceutical Co.,Ltd

Coral Drugs Private Limited

Glaxo Operations UK Ltd

Glaxo Wellcome Manufacturing Pte. Ltd

GlaxoSmithKline LLC

Haleon US Holdings LLC

Hovione FarmaCiencia SA

Hovione PharmaScience Limited

LUPIN LIMITED

Prasco Laboratories

Sicor de Mexico S.A. de C.V

Sterling Chemical Malta Ltd

STERLING SPA

Symbiotec Pharmalab Limited

TAPI Czech Industries s.r.o.

Teva Czech Industries s.r.o

Wavelength Enterprises LTD

Why It Matters

Sectors

Health

Downstream Uses

Appears in 6 drug and cosmetic product listings (FDA).

•Breo Ellipta
•Arnuity Ellipta
•Fluticasone Furoate and Vilanterol
•Fluticasone Furoate Ellipta
•Flonase Sensimist Allergy Relief
•Trelegy Ellipta

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Chemical Identity

CAS397864-44-7

PubChem CID9854489

DTXSIDDTXSID401024827

FormulaC27H29F3O6S

Mol. Weight538.6 g/mol

SMILESCC1CC2C3CC(C4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)SCF)OC(=O)C5=CC=CO5)C)O)F)C)F

Data Sources

PubChem · compound 9854489Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Fluticasone furoate (CAS 397864-44-7) https://chemicalindependence.com/chemical/397864-44-7/ PubChem: 9854489. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/9854489 FDA National Drug Code directory: CAS 397864-44-7. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293722 for CAS 397864-44-7. Reporting year: 2024. https://usatrade.census.gov/