Chloroprocaine hydrochloride

Drug ingredient

CAS 3858-89-7

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 3858-89-7 — 1 HCl

US productionNot reported

Import value, 2024$503M

Top sourceChina 25%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 292249 · basket

These shares come from HS customs code 292249, which covers 170 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 25%ChinaIN 17%IndiaSG 13%SingaporeIT 9%ItalyCH 7%Switzerland

Argentina
Poland
Portugal
Lithuania
Ukraine
Finland
Spain
Egypt
Sweden
Austria
Israel
Latvia
Belgium
Ireland
Mexico
Australia
Peru
Czech Republic
Colombia
Hong Kong

7 FDA-registered drug labelers

Edmond Pharma Srl

Fresenius Kabi USA, LLC

Harrow Eye, LLC

HF Acquisition Co LLC, DBA HealthFirst

Hikma Pharmaceuticals USA Inc.

ProPharma Distribution

Siegfried Evionnaz SA

Why It Matters

Sectors

Health

Downstream Uses

Appears in 5 drug and cosmetic product listings (FDA).

•Nesacaine MPF
•Chloroprocaine HCI
•Nesacaine
•Iheezo
•Chloroprocaine Hydrochloride

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$1110.00/gA2B Chem LLC

CountryUnited States

Pack$111.00 / 100 mg

Purity99.65%

Vendors10 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

9 more vendors

Vendor	Country	$/g	Pack	Purity
AA BLOCKS	United States	$1350.00	100 mg	99.65%
TargetMol Chemicals	China → United States	$1430.00	100 mg	99.91%
TargetMol Chemicals EU	Austria	$1900.00	50 mg	99.91%
Molnova	China	$2620.00	200 mg	99%
Aaron Chemicals LLC	Hong Kong	$2870.00	100 mg	98%
Angene Chemical	China → Hong Kong	$2900.00	100 mg	98%
MedChemExpress MCE	Sweden	$6001.60	100 mg	99.89%
Angene International Limited	United States	$8210.00	100 mg	98%
MedKoo Biosciences, Inc	United States	$15000.00	50 mg	98%

Chemical Identity

CAS3858-89-7

PubChem CID441348

DTXSIDDTXSID6048595

FormulaC13H20Cl2N2O2

Mol. Weight307.21 g/mol

SMILESCCN(CC)CCOC(=O)C1=C(C=C(C=C1)N)Cl.Cl

Data Sources

PubChem · compound 441348Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Chloroprocaine hydrochloride (CAS 3858-89-7) https://chemicalindependence.com/chemical/3858-89-7/ PubChem: 441348. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/441348 FDA National Drug Code directory: CAS 3858-89-7. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 292249 for CAS 3858-89-7. Reporting year: 2024. https://usatrade.census.gov/