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Macimorelin

Drug ingredient

CAS 381231-18-1

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 381231-18-1
US productionNot reported
Import value, 2024$174M
Top sourceItaly 69%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293790 · basket

These shares come from HS customs code 293790, which covers 10 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
IT 69%ItalyCN 22%ChinaDE 3%GermanyIN 2%IndiaJP 2%Japan
2 FDA-registered drug labelers
Aeterna Zentaris GmbH
Novo Nordisk

Why It Matters

Sectors
Health
Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

  • •Macrilen
FDA Shortage Status
No FDA shortage records

Chemical Identity

CAS381231-18-1
PubChem CID9804938
DTXSIDDTXSID601045766
FormulaC26H30N6O3
Mol. Weight474.6 g/mol
SMILESCC(C)(C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(CC3=CNC4=CC=CC=C43)NC=O)N

Data Sources

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Brief citations

Macimorelin (CAS 381231-18-1) https://chemicalindependence.com/chemical/381231-18-1/ PubChem: 9804938. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/9804938 FDA National Drug Code directory: CAS 381231-18-1. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293790 for CAS 381231-18-1. Reporting year: 2024. https://usatrade.census.gov/