bosutinib

Drug ingredient

CAS 380843-75-4

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 380843-75-4
US productionNot reported
Import value, 2024$7.6B
Top sourceIreland 61%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293359 · basket

These shares come from HS customs code 293359, which covers 295 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
IE 61%IrelandCH 30%SwitzerlandGB 2%United KingdomCN 2%ChinaIN 1%India
3 FDA-registered drug labelers
HETERO LABS LIMITED
MSN Laboratories Private Limited
SUN PHARMACEUTICAL INDUSTRIES, INC.

Why It Matters

Sectors
Health
Downstream UsesNot recorded
FDA Shortage Status
No FDA shortage records

Vendor Pricing

$39.20/gCombi-Blocks, Inc.
CountryUnited States
Pack$980.00 / 25 g
Purity97%
Vendors27 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

Chemical Identity

CAS380843-75-4
PubChem CID5328940
DTXSIDDTXSID10861568
FormulaC26H29Cl2N5O3
Mol. Weight530.4 g/mol
SMILESCN1CCN(CC1)CCCOC2=C(C=C3C(=C2)N=CC(=C3NC4=CC(=C(C=C4Cl)Cl)OC)C#N)OC

Data Sources

Brief citations

bosutinib (CAS 380843-75-4) https://chemicalindependence.com/chemical/380843-75-4/ PubChem: 5328940. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/5328940 FDA National Drug Code directory: CAS 380843-75-4. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293359 for CAS 380843-75-4. Reporting year: 2024. https://usatrade.census.gov/