ergotamine tartrate

Drug ingredient

CAS 379-79-3

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$389K

Top sourceItaly 96%

This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293962 · narrow

These shares come from HS customs code 293962, which covers 2 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IT 96%ItalyCZ 4%Czech Republic

9 FDA-registered drug labelers

Cintex Services, LLC

Cosette Pharmaceuticals, Inc.

Curia Italy S.r.l.

Medisca Inc.

Pangea Pharmaceuticals LLC

Professional Compounding Centers of America

TAPI Czech Industries s.r.o.

Teva Czech Industries s.r.o

Trifluent Pharma, LLC

Why It Matters

Sectors

Health

Downstream Uses

Appears in 4 drug and cosmetic product listings (FDA).

•ergotamine tartrate and caffeine
•Ergomar Sublingual
•Cafergot
•Migergot

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Chemical Identity

CAS379-79-3

PubChem CID9787

DTXSIDDTXSID3025253

FormulaC70H76N10O16

Mol. Weight1313.4 g/mol

SMILESCC1(C(=O)N2C(C(=O)N3CCCC3C2(O1)O)CC4=CC=CC=C4)NC(=O)C5CN(C6CC7=CNC8=CC=CC(=C78)C6=C5)C.CC1(C(=O)N2C(C(=O)N3CCCC3C2(O1)O)CC4=CC=CC=C4)NC(=O)C5CN(C6CC7=CNC8=CC=CC(=C78)C6=C5)C.C(C(C(=O)O)O)(C(=O)O)O

Data Sources

PubChem · compound 9787Retrieved 2026-04-07
EPA TSCA InventoryRetrieved 2026-04-24
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

ergotamine tartrate (CAS 379-79-3) https://chemicalindependence.com/chemical/379-79-3/ PubChem: 9787. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/9787 EPA TSCA Inventory: CAS 379-79-3. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293962 for CAS 379-79-3. Reporting year: 2024. https://usatrade.census.gov/