Betamethasone

Drug ingredient

CAS 378-44-9

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$1.1B

Top sourceSingapore 82%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293722 · basket

These shares come from HS customs code 293722, which covers 36 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

SG 82%SingaporeGB 15%United KingdomIT 2%Italy

India
Portugal
China
Mexico
Spain
Malaysia
Canada
Israel
Jordan
Belgium

3 FDA-registered drug labelers

Henan Lihua Pharmaceutical Co Ltd

Symbiotec Pharmalab Limited

Tianjin Tianyao Pharmaceuticals Co.,Ltd.

Why It Matters

Sectors

Health

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$2.26/gManchester Organics

CountryUnited Kingdom

Pack$225.61 / 100 g

Purity98%

Vendors27 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

26 more vendors

Vendor	Country	$/g	Pack	Purity
A2B Chem LLC	United States	$4.19	100 g	98%
AA BLOCKS	United States	$5.48	100 g	98%
AstaTech, Inc	United States	$13.00	25 g	98%
AK Scientific, Inc.	United States	$15.51	100 g	97%
Biopharma PEG Scientific Inc.	United States	$25.80	5 g	90%
MedChemExpress MCE	Sweden	$32.43	5 g	99.86%
AK Scientific Specialized	United States	$37.96	25 g	99%
Apexbio Technology LLC	United States	$39.00	5 g	99.95%
ALFA AESAR	Germany	$50.78	25 g	98%
Molnova	China	$74.00	500 mg	99%
MedKoo Biosciences, Inc	United States	$95.00	10 g	98%
Cayman Europe	Estonia	$104.24	5 g	98%
Fulfilled by Molport	Latvia	$120.00	100 mg	99.86%
Sigma-Aldrich (Rush Stock)	Germany	$180.57	1 g	—
Sigma-Aldrich	Germany	$180.57	1 g	—
TargetMol Chemicals	China → United States	$226.00	500 mg	99.71%
Labotest KG	Germany	$453.00	1000 mg	90%
Axon Medchem	Netherlands	$456.00	250 mg	99%
TargetMol Chemicals EU	Austria	$580.00	50 mg	99.91%
ChemFaces	China	$1500.00	20 mg	98%
Otava, Ltd. (2 weeks)	Ukraine	$2724.00	50 mg	90%
Otava, Ltd.	Ukraine	$3232.50	40 mg	90%
ChemDiv, Inc.	United States	$4070.00	100 mg	90%
Princeton BioMolecular Research (SC)	United States	$8000.00	15 mg	90%
Vitas M Chemical Limited	Hong Kong	$9000.00	10 mg	90%
TimTec, LLC (back-ordered)	United States	$33333.33	15 mg	94%

Chemical Identity

CAS378-44-9

PubChem CID9782

DTXSIDDTXSID3022667

FormulaC22H29FO5

Mol. Weight392.5 g/mol

SMILESCC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)CO)O)C)O)F)C

Data Sources

PubChem · compound 9782Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Betamethasone (CAS 378-44-9) https://chemicalindependence.com/chemical/378-44-9/ PubChem: 9782. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/9782 FDA National Drug Code directory: CAS 378-44-9. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293722 for CAS 378-44-9. Reporting year: 2024. https://usatrade.census.gov/