Heptafluoro-1-methoxypropane

CAS 375-03-1

U.S. production volumes are classified as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$117M

Import volumeZero

Top sourceIndia 29%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 290919 · basket

EPA reports by year

2023: US production Confidential · Imports Zero
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 290919, which covers 93 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IN 29%IndiaCN 25%ChinaJP 20%JapanBR 6%BrazilDE 4%Germany

South Korea
Singapore
Spain
United Arab Emirates
Netherlands
Belgium
Indonesia
Poland
Mexico
Taiwan
Slovakia

EPA-registered manufacturers (1)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Why It Matters

Sectors

ElectronicsCore Chemicals

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

Used in 2 sectors as 3 functional roles.

•Heat transferring agent in Computer and Electronic Product ManufacturingUse—non-incorporative activities
•Cleaning agent in Computer and Electronic Product ManufacturingUse—non-incorporative activities
•Solvent in All Other Chemical Product and Preparation ManufacturingUse—non-incorporative activities

Vendor Pricing

$0.64/gA2B Chem LLC

CountryUnited States

Pack$64.00 / 100 g

Purity98%

Vendors8 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

7 more vendors

Vendor	Country	$/g	Pack	Purity
AA BLOCKS	United States	$0.68	100 g	98%
Aaron Chemicals LLC	Hong Kong	$0.81	100 g	98%
Apollo Scientific UK	United Kingdom	$0.82	250 g	99.5%
Angene Chemical	China → Hong Kong	$0.88	100 g	98%
AstaTech, Inc	United States	$1.12	250 g	95%
Angene International Limited	United States	$2.00	250 g	95%
Angene	China → Hong Kong	$4266.67	30 mg	98%

Chemical Identity

CAS375-03-1

PubChem CID2774943

DTXSIDDTXSID7074909

FormulaC4H3F7O

Mol. Weight200.05 g/mol

SMILESCOC(C(C(F)(F)F)(F)F)(F)F

Data Sources

EPA CompTox (DSSTox) · DTXSID7074909Retrieved 2026-04-06
PubChem · compound 2774943Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

← Back to Dashboard ← Back to Electronics

Brief citations

Heptafluoro-1-methoxypropane (CAS 375-03-1) https://chemicalindependence.com/chemical/375-03-1/ EPA CompTox (DSSTox): DTXSID7074909. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID7074909 PubChem: 2774943. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/2774943 EPA Chemical Data Reporting: 375-03-1. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 375-03-1. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 290919 for CAS 375-03-1. Reporting year: 2024. https://usatrade.census.gov/