Flag of the United StatesAmerican Chemical Independence

3,5-Difluoroaniline

CAS 372-39-4

EPA’s 2023 records show zero U.S. production of this chemical.

Molecular structure of 372-39-4
US productionZero
Import value, 2024$3.5B
Import volumeCBI
Top sourceIreland 57%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293299 · basket

EPA reports by year
2023
US production Zero · Imports Confidential
2019
US production Confidential · Imports Confidential

These shares come from HS customs code 293299, which covers 229 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
IE 57%IrelandNL 24%NetherlandsCH 8%SwitzerlandCN 5%ChinaIT 2%Italy
EPA-registered importers (2)
Basf Se · DE Germany
Basf

Why It Matters

Sectors
Agriculture
Downstream UsesNot recorded
FDA Shortage Status
No FDA shortage records

Industrial Uses

  • •Intermediate in Pesticide, Fertilizer, and Other Agricultural Chemical ManufacturingProcessing as a reactant

Vendor Pricing

$0.27/gBiopharma PEG Scientific Inc.
CountryUnited States
Pack$135.00 / 500 g
Purity95%
Vendors29 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

28 more vendors
VendorCountry$/gPackPurity
Aaron Chemicals LLCHong Kong$0.285 kg99%
Manchester OrganicsUnited Kingdom$0.2850 g98%
Angene ChemicalChina → Hong Kong$0.31500 g99%
AA BLOCKSUnited States$0.37500 g98%
A2B Chem LLCUnited States$0.38100 g98%
Combi-Blocks, Inc.United States$0.401 kg98%
ChemsceneUnited States$0.431 kg—
BLD Pharmatech Ltd.China$0.461 kg98%
Fluorochem EUGermany$0.50500 g98%
Angene International LimitedUnited States$0.53500 g98%
BLD Pharmatech Co., LimitedUnited States$0.54500 g98%
BLD Pharmatech GmbHGermany$0.54500 g98%
Ambeed, Inc.United States$0.54500 g98%
Apollo Scientific UKUnited Kingdom$0.65500 g98%
AK Scientific SpecializedUnited States$0.66100 g98%
SynthonixUnited States$0.68500 g95%
AK Scientific, Inc.United States$0.89100 g98%
Fluorochem UKUnited Kingdom$0.9225 g98%
AstaTech, IncUnited States$0.98100 g97%
ALFA AESARGermany$7.2525 g98%
AldlabUnited States$8.281 g95%
TargetMol ChemicalsChina → United States$65.001 g—
HTS Biochemie InnovationenGermany$120.0010 g95%
Key Organics Ltd.United Kingdom$1960.00100 mg90%
Otava, Ltd. (2 weeks)Ukraine$2724.0050 mg90%
Princeton BioMolecular Research (SC)United States$2900.00100 mg90%
Vitas M Chemical LimitedHong Kong$3170.00100 mg90%
AngeneChina → Hong Kong$4266.6730 mg99%

Chemical Identity

CAS372-39-4
PubChem CID96595
DTXSIDDTXSID0059906
FormulaC6H5F2N
Mol. Weight129.11 g/mol
SMILESC1=C(C=C(C=C1F)F)N

Data Sources

← Back to Dashboard← Back to Agriculture

Brief citations

3,5-Difluoroaniline (CAS 372-39-4) https://chemicalindependence.com/chemical/372-39-4/ EPA CompTox (DSSTox): DTXSID0059906. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID0059906 PubChem: 96595. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/96595 EPA Chemical Data Reporting: 372-39-4. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 372-39-4. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 293299 for CAS 372-39-4. Reporting year: 2024. https://usatrade.census.gov/