chlorhexidine hydrochloride

Drug ingredient

CAS 3697-42-5

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 3697-42-5 — 2 HCl

US productionNot reported

Import value, 2024$240M

Top sourceChina 37%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 292529 · basket

These shares come from HS customs code 292529, which covers 64 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 37%ChinaDE 19%GermanyES 9%SpainIT 8%ItalyID 8%Indonesia

Switzerland
Canada
United Kingdom
Austria
Brazil
Israel
Australia
Hungary
Serbia
Denmark
Malaysia
Poland
Hong Kong
Ukraine
Singapore

3 FDA-registered drug labelers

DISHMAN CARBOGEN AMCIS LIMITED

Medichem S.A.

Unilab Chemicals and Pharmaceuticals Private Limited

Why It Matters

Sectors

Health

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$0.28/gCombi-Blocks, Inc.

CountryUnited States

Pack$285.00 / 1 kg

Purity97%

Vendors20 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

19 more vendors

Vendor	Country	$/g	Pack	Purity
BLD Pharmatech Ltd.	China	$0.32	1 kg	96%
Aaron Chemicals LLC	Hong Kong	$0.34	500 g	98%
Angene Chemical	China → Hong Kong	$0.34	500 g	98%
A2B Chem LLC	United States	$0.35	1 kg	98%
AA BLOCKS	United States	$0.36	1 kg	98%
BLD Pharmatech GmbH	Germany	$0.61	100 g	96%
Angene International Limited	United States	$0.64	500 g	98%
Ambeed, Inc.	United States	$0.84	25 g	96%
Cayman Europe	Estonia	$3.45	50 g	80%
MedChemExpress MCE	Sweden	$5.32	10 g	99.83%
AstaTech, Inc	United States	$5.56	25 g	95%
AK Scientific, Inc.	United States	$7.60	25 g	98%
MedKoo Biosciences, Inc	United States	$130.00	5 g	98%
Molnova	China	$350.00	100 mg	99%
Vitas M Chemical Limited	Hong Kong	$4020.00	50 mg	90%
Princeton BioMolecular Research (SC)	United States	$4200.00	50 mg	90%
Angene	China → Hong Kong	$4266.67	30 mg	98%
Key Organics Ltd.	United Kingdom	$6900.00	10 mg	97%
Interbioscreen	Hong Kong	$8464.00	50 mg	95%

Chemical Identity

CAS3697-42-5

PubChem CID9571016

DTXSIDDTXSID7047144

FormulaC22H32Cl4N10

Mol. Weight578.4 g/mol

SMILESC1=CC(=CC=C1NC(=NC(=NCCCCCCN=C(N)N=C(N)NC2=CC=C(C=C2)Cl)N)N)Cl.Cl.Cl

Data Sources

PubChem · compound 9571016Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

← Back to Dashboard ← Back to Health

Brief citations

chlorhexidine hydrochloride (CAS 3697-42-5) https://chemicalindependence.com/chemical/3697-42-5/ PubChem: 9571016. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/9571016 FDA National Drug Code directory: CAS 3697-42-5. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 292529 for CAS 3697-42-5. Reporting year: 2024. https://usatrade.census.gov/