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Rivaroxaban

Drug ingredient

CAS 366789-02-8

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 366789-02-8
US productionNot reported
Import value, 2024$6.4B
Top sourceSingapore 36%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293499 · basket

These shares come from HS customs code 293499, which covers 575 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
SG 36%SingaporeIE 23%IrelandCN 11%ChinaCH 6%SwitzerlandIN 5%India
54 FDA-registered drug labelers
A-S Medication Solutions
Alembic Pharmaceuticals Inc.
Alembic Pharmaceuticals Limited
Alivus Life Sciences Limited
Amoli Organics (A Division of Umedica Laboratories Pvt.Ltd.)
Aphena Pharma Solutions - Tennessee, LLC
Apotex Corp.
Apotex Inc.
Ascend Laboratories, LLC
Assia Chemical Industries Ltd - Teva Tech Site
Aurobindo Pharma Limited
Bajaj healthcare Ltd
Bayer AG
Biocon Limited
Camber Pharmaceuticals, Inc.
Cardinal Health 107, LLC
Changzhou Pharmaceutical Factory
Cipla Ltd.
Cohance Lifesciences Limited
Dr.Reddy's Laboratories Limited
Dr.Reddy's Laboratories, Inc.
Exelan pharmaceuticals,Inc
Florida Pharmaceutical Products, LLC
HETERO DRUGS LIMITED
HIKAL LIMITED
Indoco Remedies Limited
Janssen Pharmaceuticals, Inc.
Jubilant Biosys limited
Lee Pharma Limited
Lupin Pharmaceuticals, Inc.
LUSOMEDICAMENTA - SOCIEDADE TECNICA FARMACEUTICA, S.A.
Macleods Pharmaceuticals Limited
Medichem Manufacturing (Malta) Ltd.
Medichem S.A.
MSN Laboratories Private Limited
Nantong Chanyoo Pharmatech Co., Ltd
Neuland Laboratories Limited
Novadoz Pharmaceuticals LLC
NURAY CHEMICALS PRIVATE LIMITED
Optimus Drugs Private Limited
Patheon Inc.
Quimica Sintetica S.A.
ScieGen pharmaceuticals,Inc
Srini Pharmaceuticals Private Limited
STHREE CHEMICALS PRIVATE LIMITED
Sun Pharmaceutical Industries, Inc.
Symed Labs Limited
Teva Czech Industries s.r.o
Unichem Laboratories Limited, India
Uquifa Mexico, S.A. de C.V.
USV Private Limited
XLCare Pharmaceuticals, Inc.
Zhejiang Huahai Pharmaceutical Co., Ltd.
Zhejiang Supor Pharmaceuticals Co., Ltd

Why It Matters

Sectors
Health
Downstream Uses

Appears in 3 drug and cosmetic product listings (FDA).

  • •Xarelto
  • •Rivaroxaban
  • •rivaroxaban granule
FDA Shortage Status
No FDA shortage records

Chemical Identity

CAS366789-02-8
PubChem CID9875401
DTXSIDDTXSID3057723
FormulaC19H18ClN3O5S
Mol. Weight435.9 g/mol
SMILESC1COCC(=O)N1C2=CC=C(C=C2)N3CC(OC3=O)CNC(=O)C4=CC=C(S4)Cl

Data Sources

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Brief citations

Rivaroxaban (CAS 366789-02-8) https://chemicalindependence.com/chemical/366789-02-8/ PubChem: 9875401. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/9875401 FDA National Drug Code directory: CAS 366789-02-8. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293499 for CAS 366789-02-8. Reporting year: 2024. https://usatrade.census.gov/