Procarbazine hydrochloride

Drug ingredient

CAS 366-70-1

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$191M

Top sourceSwitzerland 35%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 292800 · basket

These shares come from HS customs code 292800, which covers 112 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CH 35%SwitzerlandIT 28%ItalyCN 12%ChinaIN 6%IndiaJP 6%Japan

Canada
Spain
Mexico
Netherlands
Poland
Malta
Norway
Ukraine
Belgium
Israel
Czech Republic
Austria
Indonesia
United Arab Emirates
Brazil
Lithuania

3 FDA-registered drug labelers

DARMERICA, LLC

F.I.S. FABBRICA ITALIANA SINTETICI S.P.A.

Leadiant Biosciences, Inc.

Why It Matters

Sectors

Health

Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

•Matulane

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$16.96/gAaron Chemicals LLC

CountryHong Kong

Pack$424.00 / 25 g

Purity98%

Vendors22 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

21 more vendors

Vendor	Country	$/g	Pack	Purity
MedKoo Biosciences, Inc	United States	$17.90	500 g	98%
Angene Chemical	China → Hong Kong	$18.16	25 g	98%
AstaTech, Inc	United States	$18.40	5 g	97%
AK Scientific Specialized	United States	$18.80	5 g	95%
Ambeed, Inc.	United States	$20.40	5 g	98%
A2B Chem LLC	United States	$23.00	1 g	98%
AK Scientific, Inc.	United States	$25.00	5 g	98%
AA BLOCKS	United States	$26.00	1 g	98%
Angene International Limited	United States	$45.60	5 g	98%
Fulfilled by Molport	Latvia	$100.00	50 mg	98%
TargetMol Chemicals	China → United States	$122.00	1 g	98.26%
Molnova	China	$285.00	200 mg	99%
MedChemExpress MCE	Sweden	$389.62	500 mg	99.66%
TargetMol Chemicals US	United States	$390.00	100 mg	98.26%
Cayman Europe	Estonia	$396.27	1 g	98%
Apexbio Technology LLC	United States	$1000.00	50 mg	98.07%
Sigma-Aldrich (Rush Stock)	Germany	$2472.95	200 mg	—
Sigma-Aldrich	Germany	$2472.95	200 mg	—
Otava, Ltd. (2 weeks)	Ukraine	$2724.00	50 mg	90%
Angene	China → Hong Kong	$4266.67	30 mg	98%
Key Organics Ltd.	United Kingdom	$6900.00	10 mg	98%

Chemical Identity

CAS366-70-1

PubChem CID9703

DTXSIDDTXSID3021190

FormulaC12H20ClN3O

Mol. Weight257.76 g/mol

SMILESCC(C)NC(=O)C1=CC=C(C=C1)CNNC.Cl

Data Sources

PubChem · compound 9703Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Procarbazine hydrochloride (CAS 366-70-1) https://chemicalindependence.com/chemical/366-70-1/ PubChem: 9703. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/9703 FDA National Drug Code directory: CAS 366-70-1. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 292800 for CAS 366-70-1. Reporting year: 2024. https://usatrade.census.gov/