Indocyanine green

Drug ingredient

CAS 3599-32-4

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 3599-32-4 — 1 Na⁺

US productionNot reported

Import value, 2024$1.4B

Top sourceIreland 33%

This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293399 · basket

These shares come from HS customs code 293399, which covers 518 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IE 33%IrelandCN 26%ChinaIN 11%IndiaDE 9%GermanyIT 4%Italy

Taiwan
Poland
Canada
Ivory Coast
Greece
Hungary
Indonesia
Latvia
Belgium
Slovakia
Czech Republic
Austria
Netherlands
Finland
Denmark
Croatia
Australia
South Africa
Sweden
Hong Kong
Malta
Singapore
Lithuania
Malaysia
Oman
Serbia

6 FDA-registered drug labelers

Aktinos pharma Private Limited

Avra Laboratories Pvt. Ltd.

Azico Biophore India Private Limited

MACSEN DRUGS

Patheon Italia S.p.A.

Sigma-Aldrich Corporation

Why It Matters

Sectors

Health

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$80.10/gAaron Chemicals LLC

CountryHong Kong

Pack$801.00 / 10 g

Purity95%

Vendors18 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

17 more vendors

Vendor	Country	$/g	Pack	Purity
Angene Chemical	China → Hong Kong	$80.70	10 g	95%
BLD Pharmatech GmbH	Germany	$129.36	25 g	95%
BLD Pharmatech Ltd.	China	$129.36	25 g	95%
A2B Chem LLC	United States	$137.20	5 g	98.77%
AA BLOCKS	United States	$160.60	5 g	95%
Ambeed, Inc.	United States	$203.20	5 g	95%
AK Scientific, Inc.	United States	$223.80	5 g	98%
Angene International Limited	United States	$350.40	5 g	98%
Key Organics Ltd.	United Kingdom	$405.40	5 g	95%
BLD Pharmatech Co., Limited	United States	$450.00	1 g	95%
AstaTech (2 weeks)	United States	$477.60	5 g	95%
TargetMol Chemicals	China → United States	$584.00	500 mg	99.96%
Apexbio Technology LLC	United States	$672.00	500 mg	99.74%
MedKoo Biosciences, Inc	United States	$930.00	5 g	98%
Sigma-Aldrich (Rush Stock)	Germany	$2072.58	500 mg	—
Sigma-Aldrich	Germany	$2072.58	500 mg	—
Angene	China → Hong Kong	$4266.67	30 mg	95%

Chemical Identity

CAS3599-32-4

PubChem CID5282412

DTXSIDDTXSID2023145

FormulaC43H47N2NaO6S2

Mol. Weight775 g/mol

SMILESCC1(C(=[N+](C2=C1C3=CC=CC=C3C=C2)CCCCS(=O)(=O)[O-])C=CC=CC=CC=C4C(C5=C(N4CCCCS(=O)(=O)[O-])C=CC6=CC=CC=C65)(C)C)C.[Na+]

Data Sources

PubChem · compound 5282412Retrieved 2026-04-07
EPA TSCA InventoryRetrieved 2026-04-24
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Indocyanine green (CAS 3599-32-4) https://chemicalindependence.com/chemical/3599-32-4/ PubChem: 5282412. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/5282412 EPA TSCA Inventory: CAS 3599-32-4. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293399 for CAS 3599-32-4. Reporting year: 2024. https://usatrade.census.gov/