1,1,2,2-Tetrafluoroethane

CAS 359-35-3

U.S. production volumes are classified as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$51M

Top sourceIndia 49%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023.

Where It Comes From

Customs basis: HS 290345 · exact

EPA reports by year

2023: US production Confidential · Imports Confidential
2019: US production Confidential · Imports Confidential

Source Countries

Country of origin for US imports, from Census customs data (2024).

IN 49%IndiaMX 24%MexicoGB 14%United KingdomCN 12%ChinaCA 1%Canada

Netherlands
South Korea

Domestic parents -- activity not disclosed (1)

EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.

Chemours

Why It Matters

Sectors

Plastics & Rubber

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

•Propellants, non-motive (blowing agents) in Plastics Product Manufacturing (40%)Processing—incorporation into formulation, mixture, or reaction product

Chemical Identity

CAS359-35-3

PubChem CID9667

DTXSIDDTXSID60883371

FormulaC2H2F4

Mol. Weight102.03 g/mol

SMILESC(C(F)F)(F)F

Data Sources

EPA CompTox (DSSTox) · DTXSID60883371Retrieved 2026-04-06
PubChem · compound 9667Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

1,1,2,2-Tetrafluoroethane (CAS 359-35-3) https://chemicalindependence.com/chemical/359-35-3/ EPA CompTox (DSSTox): DTXSID60883371. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID60883371 PubChem: 9667. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/9667 EPA Chemical Data Reporting: 359-35-3. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 359-35-3. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 290345 for CAS 359-35-3. Reporting year: 2024. https://usatrade.census.gov/