Pemetrexed disodium heptahydrate

Drug ingredient

CAS 357166-29-1

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 357166-29-1
7 H₂O · 2 Na⁺
US productionNot reported
Top sourceNo public record

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Where It Comes From

EPA and Census publish no US supply data for this chemical.

13 FDA-registered drug labelers
BSP Pharmaceuticals S.p.A.
Dr.Reddy's Laboratories Limited
Eli Lilly and Company
Eli Lilly Kinsale Limited
Jiangsu Hansoh Pharmaceutical Group Co., Ltd.
Lilly France
Meitheal Pharmaceuticals Inc.
MSN Laboratories Private Limited
ScinoPharm Taiwan Ltd.
Somerset Therapeutics LLC
SUN PHARMACEUTICAL INDUSTRIES, INC.
Waverley Pharma Inc
Wuhan Calmland Pharmaceuticals Co., Ltd.

Why It Matters

Sectors
Health
Downstream Uses

Appears in 2 drug and cosmetic product listings (FDA).

  • •Pemetrexed
  • •Alimta
FDA Shortage Status
No FDA shortage records

Chemical Identity

CAS357166-29-1
PubChem CID135564751
DTXSIDDTXSID50189238
FormulaC20H33N5Na2O13
Mol. Weight597.5 g/mol
SMILESC1=CC(=CC=C1CCC2=CNC3=C2C(=O)NC(=N3)N)C(=O)NC(CCC(=O)[O-])C(=O)[O-].O.O.O.O.O.O.O.[Na+].[Na+]

Data Sources

Brief citations

Pemetrexed disodium heptahydrate (CAS 357166-29-1) https://chemicalindependence.com/chemical/357166-29-1/ PubChem: 135564751. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/135564751 FDA National Drug Code directory: CAS 357166-29-1. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/