oxymorphone hydrochloride

Drug ingredient

CAS 357-07-3

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$103M

Top sourceAustralia 31%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293911 · basket

These shares come from HS customs code 293911, which covers 13 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

AU 31%AustraliaGB 27%United KingdomCZ 19%Czech RepublicDE 14%GermanyES 5%Spain

Taiwan
New Zealand

13 FDA-registered drug labelers

Amneal Pharmaceuticals LLC

Amneal Pharmaceuticals of New York LLC

Aurolife Pharma, LLC

Bryant Ranch Prepack

Camber Pharmaceuticals, Inc

Epic Pharma, LLC

Hikma Pharmaceuticals USA Inc.

KVK-Tech, Inc.

Noramco, LLC

Patheon Manufacturing Services LLC

SpecGx LLC

Veranova, L.P.

XLCare Pharmaceuticals, Inc.

Why It Matters

Sectors

Health

Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

•Oxymorphone Hydrochloride

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Chemical Identity

CAS357-07-3

PubChem CID5359390

DTXSIDDTXSID10189214

FormulaC17H20ClNO4

Mol. Weight337.8 g/mol

SMILESCN1CCC23C4C(=O)CCC2(C1CC5=C3C(=C(C=C5)O)O4)O.Cl

Data Sources

PubChem · compound 5359390Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

oxymorphone hydrochloride (CAS 357-07-3) https://chemicalindependence.com/chemical/357-07-3/ PubChem: 5359390. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/5359390 FDA National Drug Code directory: CAS 357-07-3. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293911 for CAS 357-07-3. Reporting year: 2024. https://usatrade.census.gov/