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Difenoxin hydrochloride

Drug ingredient

CAS 35607-36-4

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 35607-36-4
1 HCl
US productionNot reported
Import value, 2024$2M
Top sourceSwitzerland 86%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293333 · basket

These shares come from HS customs code 293333, which covers 11 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
CH 86%SwitzerlandCN 11%ChinaIT 1%ItalyUA 1%Ukraine
3 FDA-registered drug labelers
Legacy Pharma USA Inc.
Sebela Pharmaceuticals Inc.
Veranova, L.P.

Why It Matters

Sectors
Health
Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

  • •Motofen
FDA Shortage Status
No FDA shortage records

Chemical Identity

CAS35607-36-4
PubChem CID53447387
DTXSIDDTXSID30956985
FormulaC28H29ClN2O2
Mol. Weight461 g/mol
SMILESC1CN(CCC1(C2=CC=CC=C2)C(=O)O)CCC(C#N)(C3=CC=CC=C3)C4=CC=CC=C4.Cl

Data Sources

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Brief citations

Difenoxin hydrochloride (CAS 35607-36-4) https://chemicalindependence.com/chemical/35607-36-4/ PubChem: 53447387. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/53447387 FDA National Drug Code directory: CAS 35607-36-4. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293333 for CAS 35607-36-4. Reporting year: 2024. https://usatrade.census.gov/