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Fluocinonide

Drug ingredient

CAS 356-12-7

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 356-12-7
US productionNot reported
Import value, 2024$1.1B
Top sourceSingapore 82%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293722 · basket

These shares come from HS customs code 293722, which covers 36 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
SG 82%SingaporeGB 15%United KingdomIT 2%Italy
30 FDA-registered drug labelers
A-S Medication Solutions
Amneal Pharmaceuticals NY LLC
Asclemed USA, Inc.
Bausch Health US, LLC
Bryant Ranch Prepack
Cosette Pharmaceuticals, Inc.
E. Fougera & Co. a division of Fougera Pharmaceuticals, LLC
Encube Ethicals, Inc.
Farmabios S.p.A.
Glenmark Pharmaceuticals Inc., USA
LETCO MEDICAL, LLC
Lupin Pharmaceuticals,Inc.
Macleods Pharmaceuticals Limited
NorthStar RxLLC
Novel Laboratories, Inc.
NuCare Pharmaceuticals Inc.
Padagis Israel Pharmaceuticals Ltd
Preferred Pharmaceuticals Inc.
Professional Compounding Centers of America dba PCCA
Proficient Rx LP
QUAGEN PHARMACEUTICALS LLC
Sicor S.r.l.
Spectrum Laboratory Products, Inc.
Sun Pharmaceutical Industries, Inc.
SYMBIOTICA SPECIALITY INGREDIENTS SDN.BHD
Teva Pharmaceuticals USA, Inc.
Viona Pharmaceuticals Inc
Xiromed LLC
Zydus Lifesciences Limited
Zydus Pharmaceuticals USA Inc.

Why It Matters

Sectors
Health
Downstream Uses

Appears in 3 drug and cosmetic product listings (FDA).

  • •Fluocinonide
  • •Fluocinonide Cream
  • •Vanos
FDA Shortage Status
No FDA shortage records

Chemical Identity

CAS356-12-7
PubChem CID9642
DTXSIDDTXSID8045307
FormulaC26H32F2O7
Mol. Weight494.5 g/mol
SMILESCC(=O)OCC(=O)C12C(CC3C1(CC(C4(C3CC(C5=CC(=O)C=CC54C)F)F)O)C)OC(O2)(C)C

Data Sources

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Brief citations

Fluocinonide (CAS 356-12-7) https://chemicalindependence.com/chemical/356-12-7/ PubChem: 9642. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/9642 FDA National Drug Code directory: CAS 356-12-7. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293722 for CAS 356-12-7. Reporting year: 2024. https://usatrade.census.gov/