Erythromycin estolate

Drug ingredient

CAS 3521-62-8

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$16M

Top sourceChina 83%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 294150 · basket

These shares come from HS customs code 294150, which covers 8 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 83%ChinaIN 13%IndiaES 3%SpainCH 1%Switzerland

Italy
Hong Kong
Canada
Belgium

1 FDA-registered drug labeler

Calyx Chemicals & Pharmaceuticals Limited

Why It Matters

Sectors

Health

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$0.49/gCombi-Blocks, Inc.

CountryUnited States

Pack$245.00 / 500 g

Purity98%

Vendors9 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

8 more vendors

Vendor	Country	$/g	Pack	Purity
AK Scientific Specialized	United States	$1.00	10 g	95%
AstaTech, Inc	United States	$1.59	100 g	95%
MedKoo Biosciences, Inc	United States	$45.00	10 g	98%
TargetMol Chemicals	China → United States	$175.00	1 g	99.59%
TargetMol Chemicals US	United States	$238.00	500 mg	99.59%
AK Scientific, Inc.	United States	$247.00	1 g	—
MedChemExpress MCE	Sweden	$1064.80	100 mg	98%
Interbioscreen	Hong Kong	$6187.00	100 mg	92%

Chemical Identity

CAS3521-62-8

PubChem CID441371

DTXSIDDTXSID1037224

FormulaC52H97NO18S

Mol. Weight1056.4 g/mol

SMILESCCCCCCCCCCCCOS(=O)(=O)O.CCC1C(C(C(C(=O)C(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)N(C)C)OC(=O)CC)(C)O)C)C)O)(C)O

Data Sources

PubChem · compound 441371Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Erythromycin estolate (CAS 3521-62-8) https://chemicalindependence.com/chemical/3521-62-8/ PubChem: 441371. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/441371 FDA National Drug Code directory: CAS 3521-62-8. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 294150 for CAS 3521-62-8. Reporting year: 2024. https://usatrade.census.gov/