loperamide hydrochloride
Drug ingredientCAS 34552-83-5
This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.
US productionNot reported
Import value, 2024$1.3B
Top sourceChina 32%
This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.
Why supply is unknownProduction is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.
Where It Comes From
Customs basis: HS 293339 · basket
These shares come from HS customs code 293339, which covers 397 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.
Source Countries
Country of origin for US imports, from Census customs data (2024).
CN 32%ChinaIN 15%IndiaDE 10%GermanyBE 9%BelgiumCH 8%Switzerland
- Taiwan
- Ukraine
- Sweden
- Argentina
- Canada
- Finland
- Malta
- Israel
- Netherlands
- Denmark
- United Arab Emirates
- Mexico
- Brunei
- Slovakia
- Australia
- South Africa
- Poland
- Latvia
- Lithuania
- Estonia
- Slovenia
- Czech Republic
- Croatia
- Hong Kong
116 FDA-registered drug labelers
A-S Medication Solutions
Advagen Pharma Ltd.,
Advanced Rx LLC
Albertsons Companies
Allegiant Health
allphamed Pharbil Arzneimittel GmbH
Amazon.com Services LLC
American Health Packaging
American Sales Company
AMERISOURCE BERGEN
Aphena Pharma Solutions - Tennessee, LLC
ARMY AND AIR FORCE EXCHANGE SERVICE
ATLANTIC BIOLOGICALS CORP.
Aurobindo Pharma Limited
Aurohealth LLC
AvPAK
Better Living Brands, LLC
BI-MART
BIONPHARMA INC.
BJWC
Bryant Ranch Prepack
Camber Consumer Care Inc
CARDINAL HEALTH
Cardinal Health 107, LLC
Cardinal Health 110, LLC. dba Leader
Chain Drug Consortium
Chain Drug Consortium, LLC
CHAIN DRUG MARKETING ASSOCIATION INC
Cintas Corp
CVS Pharmacy
CVS Pharmacy, Inc.
Discount Drug Mart
DISCOUNT DRUG MART, INC.
DOLGENCORP INC
DOLGENCORP, LLC
Dr. Reddy's Laboratories Inc.
Edenbridge Pharmaceuticals LLC.
Family Dollar Services Inc
Family Dollar Stores, LLC
First Aid Direct
Fred's Inc.
FSA store INC
Geri-Care Pharmaceutical Corp
Golden State Medical Supply, Inc.
Granules India Ltd
Grocery Outlet
Guardian Drug Company
H E B
Harris Teeter, LLC
HyVee Inc
IMO-GEN LABS LLC
Janssen Pharmaceutica NV
Kenvue Brands LLC
KROGER COMPANY
L. Perrigo Company
L.N.K. International, Inc.
Lil' Drug Store Products, Inc.
Major Pharmaceuticals
Marc Glassman, Inc.
MARKSANS PHARMA LIMITED
Medisca Inc.
Medline Industries, LP
MEIJER DISTRIBUTION INC
Mylan Institutional Inc.
Mylan Pharmaceuticals Inc.
Navajo Manufacturing Company Inc.
NCS HealthCare of KY, LLC dba Vangard Labs
NORTHEAST PHARMA
NorthStar Rx LLC
Northwind Health Company, LLC
NuCare Pharmaceuticals, Inc.
Ohm Laboratories Inc.
Olon S.p.A.
Patheon Softgels Inc.
PD-Rx Pharmaceuticals, Inc.
PMC ISOCHEM
Precision Dose, Inc.
Preferred Pharmaceuticals Inc.
Premier Value Alliance LLC
Professional Compounding Centers of America
Professional Compounding Centers of America dba PCCA
Proficient Rx LP
PUBLIX SUPER MARKETS INC
Redpharm Drug
Redpharm Drug Inc
REMEDYREPACK INC.
Rite Aid Corporation
Safecor Health LLC
Safeway
SDA Laboratories, Inc.
SICOR Societa' Italiana Corticosteroidi s.r.l.
Sportpharm LLC
Sportpharm, Inc. dba Sportpharm
STRATEGIC SOURCING SERVICES
Strategic Sourcing Services LLC
TARGET Corporation
Teva Pharmaceuticals USA, Inc.
TOP CARE (Topco Associates LLC)
Topco Associates LLC
Unifirst First Aid Corporation
United Natural Foods, Inc. dba UNFI
VALU MERCHANDISERS COMPANY
VAMSI LABS LIMITED.
Vasudha Pharma Chem Limited
Viona Pharmaceuticals Inc
Wal-Mart Stores Inc
WALGREEN CO.
Walgreen Company
WALGREENS
WALMART INC.
WinCo Foods
WinCo Foods, LLC
Xenex Laboratories Inc
YYBA CORP
Zee Medical Inc
Zydus Lifesciences Limited
Why It Matters
Sectors
Health
Downstream Uses
Appears in 54 drug and cosmetic product listings (FDA).
- •Loperamide Hydrochloride
- •basic care loperamide hydrochloride
- •Loperamide Hydrochloride and Simethicone
- •Anti-Diarrheal
- •Anti Diarrheal Anti Gas
- •topcare anti diarrheal
- •CareOne Diarrhea Control
- •equate diarrhea control
Show all 54
- •Imodium A-D
- •dg health anti diarrheal
- •Handy Solutions Anti-Diarrheal
- •leader anti diarrheal
- •Welmate Anti Diarrheal Loperamide HCl Softgels
- •Good Sense Anti Diarrheal Anti Gas
- •injoy diarrhea relief
- •topcare loperamide hydrochloride
- •First Aid Direct Anti-Diarrheal
- •Anti-Diarrheal, 24/7 Life by 7-Eleven
- •anti diarrheal and anti gas
- •up and up anti diarrheal anti gas
- •signature care anti diarrheal anti gas
- •berkley and jensen anti diarrheal
- •foster and thrive anti diarrheal anti gas
- •good neighbor pharmacy anti diarrheal
- •Good Sense antidiarrheal
- •Anti-Diarrheal/Anti-Gas Multi-Symptom Relief
- •Medique Diamode
- •antidiarrheal multi symptom relief
- •Lil Drug Store Anti-Diarrheal
- •Up and Up anti diarrheal
- •CareOne Diarrhea and Gas Control
- •Private Label Distributor
- •Equate Loperamide Hydrochloride
- •Imodium Multi-Symptom Relief
- •dg health anti diarrheal anti gas
- •Anti-Diarrheal, CVP Health
- •Welmate Anti Diarrheal Loperamide HCl
- •signature care anti diarrheal
- •good neighbor pharmacy loperamide hydrochloride
- •foster and thrive anti-diarrheal
- •Basic Care Loperamide Hydrochloride and Simethicone
- •Anti-Diarrheal, Caseys 4good
- •Anti-Diarrheal/Anti-Gas Caplets
- •Equate Anti Diarrheal Anti Gas Multi-Symptom Relief
- •Loperamide Hydrochloride 2mg
- •equaline loperamide hydrochloride
- •equaline anti diarrheal plus anti gas
- •anti diarrheal plus anti gas
- •good neighbor pharmacy anti diarrheal anti gas
- •Loperamide HCl
- •Loperamide HCl and Simethicone
- •Loperamide Hydrochloride, Simethicone
- •Anti-Diarrheal, Circle K
- •Amazon Basic CARE Loperamide Hydrochloride
FDA Shortage Status
Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."
No FDA shortage records
Vendor Pricing
$2.32/gCombi-Blocks, Inc.
CountryUnited States
Pack$1160.00 / 500 g
Purity98%
Vendors20 available
Prices reflect listed pack sizes. Small research packs run far above bulk rates.
19 more vendors
| Vendor | Country Supplier country. Where available, shows shipping origin. When the supplier ships from a different country than where they are registered, both are shown. Most suppliers show registration country only. | $/g | Pack | Purity |
|---|---|---|---|---|
| A2B Chem LLC | United States | $2.46 | 500 g | 98% |
| AA BLOCKS | United States | $2.59 | 500 g | 98% |
| AK Scientific Specialized | United States | $2.90 | 100 g | 95% |
| AK Scientific, Inc. | United States | $3.89 | 100 g | 98% |
| Aaron Chemicals LLC | Hong Kong | $5.05 | 100 g | 98% |
| Angene Chemical | China → Hong Kong | $5.41 | 100 g | 98% |
| Angene International Limited | United States | $9.24 | 25 g | 98% |
| Fulfilled by Molport | Latvia | $10.00 | 1 g | 98% |
| AstaTech, Inc | United States | $25.60 | 5 g | 95% |
| Sigma-Aldrich (Rush Stock) | Germany | $29.26 | 25 g | — |
| Sigma-Aldrich | Germany | $29.26 | 25 g | — |
| MedKoo Biosciences, Inc | United States | $54.00 | 25 g | 98% |
| CliniSciences GmbH | Switzerland | $60.63 | 1 g | 99% |
| TargetMol Chemicals | China → United States | $109.00 | 1 g | 99.99% |
| Molnova | China | $138.00 | 500 mg | 99% |
| MedChemExpress MCE | Sweden | $246.84 | 500 mg | 99.84% |
| Axon Medchem | Netherlands | $1200.00 | 50 mg | 100% |
| Angene | China → Hong Kong | $4266.67 | 30 mg | 98% |
| TimTec, LLC | United States | $16000.00 | 30 mg | 90% |
Chemical Identity
CAS34552-83-5
PubChem CID71420
DTXSIDDTXSID00880006
FormulaC29H34Cl2N2O2
Mol. Weight513.5 g/mol
SMILESCN(C)C(=O)C(CCN1CCC(CC1)(C2=CC=C(C=C2)Cl)O)(C3=CC=CC=C3)C4=CC=CC=C4.Cl
Data Sources
- PubChem · compound 71420Retrieved 2026-04-07
- FDA National Drug Code directoryRetrieved 2026-04-25
- FDA National Drug Code directoryRetrieved 2026-04-07
- US Census international tradeReporting year: 2024 · Retrieved 2026-10-04
Brief citations
loperamide hydrochloride (CAS 34552-83-5) https://chemicalindependence.com/chemical/34552-83-5/ PubChem: 71420. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/71420 FDA National Drug Code directory: CAS 34552-83-5. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293339 for CAS 34552-83-5. Reporting year: 2024. https://usatrade.census.gov/