propafenone hydrochloride

Drug ingredient

CAS 34183-22-7

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 34183-22-7 — 1 HCl

US productionNot reported

Top sourceNo public record

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Where It Comes From

EPA and Census publish no US supply data for this chemical.

20 FDA-registered drug labelers

A-S Medication Solutions

Actavis Pharma, Inc.

American Health Packaging

ANI Pharmaceuticals, Inc.

Aurobindo Pharma Limited

Bryant Ranch Prepack

Erregierre SpA

Fermion Oy

Glenmark Pharmaceuticals Inc., USA

Golden State Medical Supply, Inc.

Northstar Rx LLC

PharmaZell GmbH

PROCOS S.p.A.

Rising Pharma Holdings, Inc.

SCI PHARMTECH, INC.

Strides Pharma Science Limited

Upsher-Smith Laboratories, LLC

Vitruvias Therapeutics

Zydus Lifesciences Limited

Zydus Pharmaceuticals (USA) Inc.

Why It Matters

Sectors

Health

Downstream Uses

Appears in 2 drug and cosmetic product listings (FDA).

•Propafenone Hydrochloride
•Propafenone HCl

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No Shortage

Shortage History

Rows group FDA shortage filings by drug product. Each manufacturer makes its own FDA shortage filing, so one product can carry several reports at once: Available, Limited Availability, Unavailable or to be discontinued.

to be discontinued
Propafenone Hydrochloride Capsule, Extended Release
Shortage listed since May 14, 2025

See all current drug shortages

Vendor Pricing

$0.47/gAaron Chemicals LLC

CountryHong Kong

Pack$47.00 / 100 g

Purity95%

Vendors23 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

22 more vendors

Vendor	Country	$/g	Pack	Purity
Angene Chemical	China → Hong Kong	$0.49	100 g	95%
A2B Chem LLC	United States	$1.78	500 g	99%
AA BLOCKS	United States	$1.88	500 g	99%
Combi-Blocks, Inc.	United States	$2.05	100 g	98%
Ambeed, Inc.	United States	$2.40	100 g	99%
AK Scientific Specialized	United States	$2.40	100 g	95%
AK Scientific, Inc.	United States	$3.21	100 g	98%
Angene International Limited	United States	$5.28	100 g	98%
AstaTech, Inc	United States	$14.92	25 g	95%
Cayman Europe	Estonia	$22.02	10 g	98%
MedChemExpress MCE	Sweden	$29.77	5 g	98.47%
Sigma-Aldrich (Rush Stock)	Germany	$34.81	5 g	—
Sigma-Aldrich	Germany	$34.81	5 g	—
Apexbio Technology LLC	United States	$55.00	1 g	99.73%
TargetMol Chemicals	China → United States	$145.00	200 mg	99.67%
MedKoo Biosciences, Inc	United States	$250.00	5 g	98%
CliniSciences GmbH	Switzerland	$322.50	100 mg	98%
Axon Medchem	Netherlands	$1440.00	50 mg	100%
Otava, Ltd. (2 weeks)	Ukraine	$2724.00	50 mg	90%
Princeton BioMolecular Research (SC)	United States	$4200.00	50 mg	90%
Angene	China → Hong Kong	$4266.67	30 mg	95%
Key Organics Ltd.	United Kingdom	$6900.00	10 mg	97%

Chemical Identity

CAS34183-22-7

PubChem CID36708

DTXSIDDTXSID101017233

FormulaC21H28ClNO3

Mol. Weight377.9 g/mol

SMILESCCCNCC(COC1=CC=CC=C1C(=O)CCC2=CC=CC=C2)O.Cl

Data Sources

PubChem · compound 36708Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA Drug ShortagesRetrieved 2026-10-04

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Brief citations

propafenone hydrochloride (CAS 34183-22-7) https://chemicalindependence.com/chemical/34183-22-7/ PubChem: 36708. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/36708 FDA National Drug Code directory: CAS 34183-22-7. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA Drug Shortages: CAS 34183-22-7. Retrieved 2026-10-04. https://www.accessdata.fda.gov/scripts/drugshortages/