Esketamine hydrochloride
Drug ingredientCAS 33643-47-9
This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.
US productionNot reported
Top sourceNo public record
This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.
Why supply is unknownWhere It Comes From
EPA and Census publish no US supply data for this chemical.
7 FDA-registered drug labelers
Arevipharma GmbH
CU Chemie Uetikon GmbH
Janssen Pharmaceuticals Inc.
Janssen Pharmaceuticals Sciences Unlimited Company
Maithri Drugs Private Limited
Nortec Quimica SA
Supriya Lifescience Limited
Why It Matters
Sectors
Health
Downstream Uses
Appears in 1 drug and cosmetic product listings (FDA).
- •Spravato
FDA Shortage Status
Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."
No FDA shortage records
Chemical Identity
CAS33643-47-9
PubChem CID44632368
DTXSIDDTXSID601027734
FormulaC13H17Cl2NO
Mol. Weight274.18 g/mol
SMILESCNC1(CCCCC1=O)C2=CC=CC=C2Cl.Cl
Data Sources
- PubChem · compound 44632368Retrieved 2026-04-07
- FDA National Drug Code directoryRetrieved 2026-04-25
- FDA National Drug Code directoryRetrieved 2026-04-07
Brief citations
Esketamine hydrochloride (CAS 33643-47-9) https://chemicalindependence.com/chemical/33643-47-9/ PubChem: 44632368. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/44632368 FDA National Drug Code directory: CAS 33643-47-9. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/