Perfluoro-2-butyltetrahydrofuran

CAS 335-36-4

Companies reported imports and no US production of this chemical to EPA for 2023.

US productionZero

Import value, 2024$64M

Import volume27.8K lb

Import dependency100%

Top sourceChina 37%

Production is reported production, not a complete census of factories. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Perfluoro-2-butyltetrahydrofuran · US import value by year

Peak 2013: $271M · 2024: $64M · 2025: $127M

Where It Comes From

Customs basis: HS 293219 · basket

EPA reports by year

2023: US production Zero · Imports 27.8K lb
2019: US production Zero · Imports 55.6K lb

These shares come from HS customs code 293219, which covers 136 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 37%ChinaIT 23%ItalyJP 20%JapanIN 12%IndiaES 2%Spain

Belgium
Germany
Netherlands
Canada
Mexico
Slovakia
Malaysia
Portugal
Taiwan
Sweden
Latvia
Israel

EPA-registered importers (1)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Quaker Houghton

Why It Matters

Sectors

Energy

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

•Lubricating agent in Petroleum Lubricating Oil and Grease Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product

Vendor Pricing

$0.94/gAaron Chemicals LLC

CountryHong Kong

Pack$94.00 / 100 g

Purity95%

Vendors10 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

9 more vendors

Vendor	Country	$/g	Pack	Purity
Angene Chemical	China → Hong Kong	$0.96	100 g	97%
AA BLOCKS	United States	$1.76	25 g	—
Combi-Blocks, Inc.	United States	$3.00	250 g	95%
AK Scientific, Inc.	United States	$4.56	25 g	—
A2B Chem LLC	United States	$4.92	25 g	—
Angene International Limited	United States	$8.44	25 g	—
Fluorochem UK	United Kingdom	$20.59	5 g	95%
AstaTech (2 weeks)	United States	$48.00	1 g	95%
Angene	China → Hong Kong	$4266.67	30 mg	95%

Chemical Identity

CAS335-36-4

PubChem CID78976

DTXSIDDTXSID60871632

FormulaC8F16O

Mol. Weight416.06 g/mol

SMILESC1(C(C(OC1(C(C(C(C(F)(F)F)(F)F)(F)F)(F)F)F)(F)F)(F)F)(F)F

Data Sources

EPA CompTox (DSSTox) · DTXSID60871632Retrieved 2026-04-06
PubChem · compound 78976Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Perfluoro-2-butyltetrahydrofuran (CAS 335-36-4) https://chemicalindependence.com/chemical/335-36-4/ EPA CompTox (DSSTox): DTXSID60871632. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID60871632 PubChem: 78976. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/78976 EPA Chemical Data Reporting: 335-36-4. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 335-36-4. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 293219 for CAS 335-36-4. Reporting year: 2024. https://usatrade.census.gov/