Buspirone hydrochloride

Drug ingredient

CAS 33386-08-2

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 33386-08-2
1 HCl
US productionNot reported
Import value, 2024$7.6B
Top sourceIreland 61%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293359 · basket

These shares come from HS customs code 293359, which covers 295 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
IE 61%IrelandCH 30%SwitzerlandGB 2%United KingdomCN 2%ChinaIN 1%India
50 FDA-registered drug labelers
A-S Medication Solutions
Accord Healthcare Inc.
Advagen Pharma Ltd
Advanced Rx of Tennessee, LLC
Advanced Rx Pharmacy of Tennessee, LLC
AiPing Pharmaceutical, Inc.
American Health Packaging
Aphena Pharma Solutions - Tennessee, LLC
APNAR PHARMA LP
Asclemed USA, Inc.
Aurobindo Pharma Limited
AvPAK
Boswell Pharmacy Services d/b/a BPS Wholesale
Boswell Pharmacy Services LLC d/b/a BPS Wholesale
Bryant Ranch Prepack
Cardinal Health 107, LLC
Cohance Lifesciences Limited
DIRECT RX
EPIC PHARMA, LLC
Excella GmbH & Co. KG
Fermion Oy
Golden State Medical Supply, Inc.
Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.
LETCO MEDICAL, LLC
Maithri Laboratories Private Limited
Major Pharmaceuticals
Medilux Laboratories Private Limited
Mylan Institutional Inc.
Mylan Pharmaceuticals Inc.
NCS HealthCare of KY, LLC dba Vangard Labs
Nivagen Pharmaceuticals Inc.
Northwind Health Company, LLC
NuCare Pharmaceuticals, Inc.
Oxford Pharmaceuticals, LLC
PD-Rx Pharmaceuticals, Inc.
Preferred Pharmaceuticals Inc.
Professional Compounding Centers of America
Proficient Rx LP
Radha Pharmaceuticals, Inc.
REMEDYREPACK INC.
Safecor Health, LLC
SOLARA ACTIVE PHARMA SCIENCES LIMITED
Spectrum Laboratory Products, Inc.
Strides Pharma Inc.
Strides Pharma Science Limited
Teva Pharmaceuticals USA, Inc.
Unichem Laboratories Limited, India
Unichem Pharmaceuticals (USA), Inc.
Zydus Lifesciences Limited
Zydus Pharmaceuticals USA Inc.

Why It Matters

Sectors
Health
Downstream Uses

Appears in 2 drug and cosmetic product listings (FDA).

  • •Buspirone hydrochloride
  • •Buspirone HCL
FDA Shortage Status
No FDA shortage records

Vendor Pricing

$24.60/gAaron Chemicals LLC
CountryHong Kong
Pack$246.00 / 10 g
Purity99%
Vendors25 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

Chemical Identity

CAS33386-08-2
PubChem CID36431
DTXSIDDTXSID1037193
FormulaC21H32ClN5O2
Mol. Weight422 g/mol
SMILESC1CCC2(C1)CC(=O)N(C(=O)C2)CCCCN3CCN(CC3)C4=NC=CC=N4.Cl

Data Sources

Brief citations

Buspirone hydrochloride (CAS 33386-08-2) https://chemicalindependence.com/chemical/33386-08-2/ PubChem: 36431. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/36431 FDA National Drug Code directory: CAS 33386-08-2. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293359 for CAS 33386-08-2. Reporting year: 2024. https://usatrade.census.gov/