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(3-Chloro-2-hydroxypropyl)trimethylammonium chloride

CAS 3327-22-8

U.S. production volumes are classified as confidential business information.

Molecular structure of 3327-22-8
1 Cl⁻
US productionCBI
Import value, 2024$108M
Top sourceChina 14%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 292390 · basket

EPA reports by year
2023
US production Confidential · Imports Confidential
2019
US production Confidential · Imports Confidential

These shares come from HS customs code 292390, which covers 130 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
CN 14%ChinaGB 13%United KingdomDE 11%GermanyIN 10%IndiaTW 10%Taiwan
EPA-registered manufacturers (2)
Dow Chemical
Tremco Cpg Manufacturing
Domestic parents -- activity not disclosed (1)
Skw Quab Chemical
EPA-registered importers (3)
Samsung C&T · KR South Korea
Brenntag
Samsung C&T America

Why It Matters

Sectors
HealthEnergyPaper & PrintingCore Chemicals
Downstream UsesNot recorded
FDA Shortage Status
No FDA shortage records

Industrial Uses

Used in 4 sectors as 2 functional roles.

  • •Intermediate in All Other Chemical Product and Preparation Manufacturing (20%)Processing—repackaging
  • •Intermediate in Pharmaceutical and Medicine Manufacturing (10%)Processing as a reactant
  • •Intermediate in Paper Manufacturing (50%)Processing as a reactant
  • •Intermediate in Oil and Gas Drilling, Extraction, and Support activities (0%)Processing—incorporation into formulation, mixture, or reaction product
  • •Ion exchange agent in All Other Chemical Product and Preparation Manufacturing (100%)Processing as a reactant

Vendor Pricing

$0.02/gAaron Chemicals LLC
CountryHong Kong
Pack$11.00 / 500 g
Purity69%
Vendors13 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

12 more vendors
VendorCountry$/gPackPurity
Angene ChemicalChina → Hong Kong$0.03500 g69%
A2B Chem LLCUnited States$0.041 kg95%
AA BLOCKSUnited States$0.041 kg65%
BLD Pharmatech Co., LimitedUnited States$0.051 kg65%
BLD Pharmatech GmbHGermany$0.051 kg65%
BLD Pharmatech Ltd.China$0.051 kg65%
Ambeed, Inc.United States$0.051 kg65%
ChemsceneUnited States$0.051 kg—
SynthonixUnited States$0.08500 g65%
AK Scientific, Inc.United States$0.55100 g98%
Angene International LimitedUnited States$1.20100 g98%
AngeneChina → Hong Kong$4266.6730 mg69%

Chemical Identity

CAS3327-22-8
PubChem CID18732
DTXSIDDTXSID3027534
FormulaC6H15Cl2NO
Mol. Weight188.09 g/mol
SMILESC[N+](C)(C)CC(CCl)O.[Cl-]

Data Sources

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Brief citations

(3-Chloro-2-hydroxypropyl)trimethylammonium chloride (CAS 3327-22-8) https://chemicalindependence.com/chemical/3327-22-8/ EPA CompTox (DSSTox): DTXSID3027534. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID3027534 PubChem: 18732. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/18732 EPA Chemical Data Reporting: 3327-22-8. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 3327-22-8. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 292390 for CAS 3327-22-8. Reporting year: 2024. https://usatrade.census.gov/